Primaquine EP Impurity B CAS 85-81-4
| CAS No. | 85-81-4 |
| Molecular Formula | C10H8N2O3 |
| Molecular Weight | 204.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 204.18 g/mol gives Primaquine EP Impurity B distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Primaquine EP Impurity B (CAS 85-81-4), a pharmacopoeial impurity reference standard (molecular formula C10H8N2O3, MW 204.18 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C10H8N2O3, Primaquine EP Impurity B contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 204.18 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Primaquine EP Impurity B meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H8N2O3 |
| Molecular Weight | 204.18 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 2 |
Related Primaquine Standards
- Primaquine EP Impurity C (CAS 90-52-8)
- Primaquine - API Standards (CAS 90-34-6)
- Primaquine Impurity 4 (CAS 2732404-25-8)
- Primaquine-d3 Diphosphate (CAS 1318852-20-8)
- Primaquine Impurity 3 (CAS 57695-07-5)
- Primaquine impurity 3 (CAS CATO-C4X-26353)
- Primaquine Impurity 1 (CAS 47136-26-5)
- Primaquine EP Impurity D (CAS 83532-78-9)
Recommended Standards
- 6-Methoxy-7-nitroquinoline (CAS 855760-37-1)
- 6-Methyl-3-nitroquinolin-4-ol (CAS 256923-67-8)
- 6-Methoxy-5-nitroquinoline (CAS 6623-91-2)
- 6-Methyl-4-nitroquinoline 1-oxide (CAS 715-48-0)
- Amikacin Impurity 18 (CAS 1793053-90-3)
- Vazegepant Impurity N72 (CAS 855778-84-6)
- Amorolfine Impurity 55 (CAS CATO-C4X-154255)
- 3-(2-Ethoxy-2-oxoethylidene)-4-oxo-1-piperidinecarboxylic Acid 1,1-Dimethylethyl Ester (CAS 1395498-37-9)
- 6-Chloro-4-(trifluoromethyl)nicotinamide (CAS 1201186-88-0)
- n1-((5-Bromothiophen-2-yl)methyl)-n2,n2-diethylethane-1,2-diamine (CAS 1019539-50-4)
- N-(1-Cyanocyclohexyl)-2-((5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)thio)propanamide (CAS 796125-87-6)
- 6-Bromo-8-phenyl-[1,2,4]triazolo[4,3-a]pyridine (CAS 1202277-96-0)
- 1-(3,5-Dimethyl-2-thioxo-2,3-dihydro-1H-imidazol-4-yl)ethanone (CAS 877305-15-2)
- Tirzepatide (CAS 2023788-19-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com