(2-Methyl-4-(trifluoromethoxy)phenyl)boronic acid CAS 850033-39-5

Purity 97%+In StockPharmaceutical Standards
CAS No.850033-39-5
Molecular FormulaC8H8BF3O3
Molecular Weight219.95 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(2-Methyl-4-(trifluoromethoxy)phenyl)boronic acid CAS 850033-39-5 chemical structure

Description

The occurrence of (2-Methyl-4-(trifluoromethoxy)phenyl)boronic acid is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

(2-Methyl-4-(trifluoromethoxy)phenyl)boronic acid (CAS 850033-39-5), molecular formula C8H8BF3O3 and molecular weight 219.95 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, (2-Methyl-4-(trifluoromethoxy)phenyl)boronic acid is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 219.95 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC8H8BF3O3
Molecular Weight219.95 g/mol
Purity97%+
StorageStore in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)3.5
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1987
Halogen ContentF-containing

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Why CATO?