3-Amino-4-chlorophenylboronic Acid Pinacol Ester CAS 850567-56-5

Purity 97%+In StockPharmaceutical Standards
CAS No.850567-56-5
Molecular FormulaC12H17BClNO2
Molecular Weight253.53 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-Amino-4-chlorophenylboronic Acid Pinacol Ester CAS 850567-56-5 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 253.53 g/mol gives 3-Amino-4-chlorophenylboronic Acid Pinacol Ester distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies 3-Amino-4-chlorophenylboronic Acid Pinacol Ester (CAS 850567-56-5), a certified reference material (molecular formula C12H17BClNO2, MW 253.53 g/mol) for analytical method development and quality control.

The molecular framework of 3-Amino-4-chlorophenylboronic Acid Pinacol Ester (C12H17BClNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 3-Amino-4-chlorophenylboronic Acid Pinacol Ester meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC12H17BClNO2
Molecular Weight253.53 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)4.5
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Halogen ContentCl-containing
Nitrogen Atoms1

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