4-(4-Chlorophenyl)-3-(thiophen-2-yl)-2,5-dihydrofuran-2-one CAS 851169-29-4
| CAS No. | 851169-29-4 |
| Molecular Formula | C14H9ClO2S |
| Molecular Weight | 276.74 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-(4-Chlorophenyl)-3-(thiophen-2-yl)-2,5-dihydrofuran-2-one is closely related to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, a polycyclic aromatic system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-(4-Chlorophenyl)-3-(thiophen-2-yl)-2,5-dihydrofuran-2-one (CAS 851169-29-4) is a high-purity analytical reference standard with the molecular formula C14H9ClO2S and a molecular weight of 276.74 g/mol.
Structurally, 4-(4-Chlorophenyl)-3-(thiophen-2-yl)-2,5-dihydrofuran-2-one (C14H9ClO2S) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, a polycyclic aromatic system. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 276.74 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-(4-Chlorophenyl)-3-(thiophen-2-yl)-2,5-dihydrofuran-2-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H9ClO2S |
| Molecular Weight | 276.74 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 1 |
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- 4-[2-(2-Chlorophenyl)-1,3-thiazol-4-yl]-5-methyl-1,2-oxazole (CAS 478049-20-6)
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Recommended Standards
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- 3-Chloro-5-((2-fluorobenzyl)sulfinyl)-1,2,4-thiadiazole (CAS 486997-72-2)
- 3-(4-Chlorobenzyl)thieno[2,3-d]pyrimidin-4(3H)-one (CAS 338777-24-5)
- 1-methanesulfonylpyrrolidin-3-ol (CAS 1025772-40-0)
- 3-(3,4-Dimethoxyphenyl)-5-((4-fluorobenzyl)thio)-4H-1,2,4-triazol-4-amine (CAS 577791-50-5)
- Methyl (2Z)-2-(benzenesulfonyl)-3-[(3,4-difluorophenyl)amino]prop-2-enoate (CAS 1564076-40-9)
- 1-[4-(2,4-dioxohexahydropyrimidin-1-yl)phenyl]azetidine-3-carbaldehyde (CAS 2919016-70-7)
- 2-Cyano-4-fluorobenzaldehyde (CAS 77532-90-2)
- 3-(2-methyl-1H-benzimidazol-1-yl)propan-1-amine (CAS 79837-02-8)
- 6-Methyl-8-nitro-4-oxo-4H-chromene-3-carbaldehyde (CAS 879559-54-3)
- 3-(Oxan-4-yl)piperidine (CAS 1369346-64-4)
- Methyl 2-amino-3-(4-bromo-2-fluorophenyl)propanoate (CAS 1339204-02-2)
- Peptide Impurity 24 (CAS CATO-CPTD788824)
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