N-(4-(4-Methoxyphenyl)thiazol-2-yl)-4-(thiophen-2-yl)butanamide CAS 851206-59-2

Purity 97%+In StockPharmaceutical Standards
CAS No.851206-59-2
Molecular FormulaC18H18N2O2S2
Molecular Weight358.48 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N-(4-(4-Methoxyphenyl)thiazol-2-yl)-4-(thiophen-2-yl)butanamide CAS 851206-59-2 chemical structure

Description

The occurrence of N-(4-(4-Methoxyphenyl)thiazol-2-yl)-4-(thiophen-2-yl)butanamide is closely related to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

N-(4-(4-Methoxyphenyl)thiazol-2-yl)-4-(thiophen-2-yl)butanamide (CAS 851206-59-2) is a high-purity analytical reference standard with the molecular formula C18H18N2O2S2 and a molecular weight of 358.48 g/mol.

N-(4-(4-Methoxyphenyl)thiazol-2-yl)-4-(thiophen-2-yl)butanamide (C18H18N2O2S2) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC18H18N2O2S2
Molecular Weight358.48 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Nitrogen Atoms2
Sulfur Atoms2

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