5-{[2-chloro-5-(trifluoromethyl)phenyl]methyl}-1,3-thiazol-2-amine CAS 851398-28-2
| CAS No. | 851398-28-2 |
| Molecular Formula | C11H8ClF3N2S |
| Molecular Weight | 292.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 5-{[2-chloro-5-(trifluoromethyl)phenyl]methyl}-1,3-thiazol-2-amine (CAS 851398-28-2), a certified reference material (molecular formula C11H8ClF3N2S, MW 292.71 g/mol) for analytical method development and quality control.
5-{[2-chloro-5-(trifluoromethyl)phenyl]methyl}-1,3-thiazol-2-amine (C11H8ClF3N2S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures 5-{[2-chloro-5-(trifluoromethyl)phenyl]methyl}-1,3-thiazol-2-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H8ClF3N2S |
| Molecular Weight | 292.71 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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Recommended Standards
- 4-(Benzyloxy)-3-chloro-5-methoxybenzoic acid (CAS 857599-19-0)
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- 3-[(4-Chlorophenoxy)methyl]-4-methoxybenzoic acid (CAS 438221-04-6)
- Benzoic acid, 5-(chlorosulfonyl)-4-cyclopropyl-2-fluoro-, methyl ester (CAS 2897543-95-0)
- (S)-5-Methyl-2-thioxoimidazolidin-4-one (CAS 37712-67-7)
- 1-iso-Propylimino-4,4,4-trifluoro-3-trifluoromethylbutan-3-ol (CAS 824954-68-9)
- Ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate hydrobromide (CAS 1177092-98-6)
- 3-Bromo-2-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 1402227-31-9)
- 5-Cyclopropylisoxazole-4-carbaldehyde (CAS 1557510-07-2)
- Ethyl 4-(4-methylpiperidin-1-yl)benzoate (CAS 1160246-03-6)
- (1-Cyclopentyl-2,2,2-trifluoroethyl)benzene (CAS 1186195-02-7)
- (7-Amino-2,2-difluorobenzo[d][1,3]dioxol-4-yl)dimethylphosphine oxide (CAS 2903924-00-3)
- 5-Amino-4-methylnicotinic acid (CAS 890092-44-1)
- D-[His]1-Semaglutide X TFA salt (CAS CATO-CPTD788634)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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