Rosuvastatin Impurity 206 CAS 851440-19-2
| CAS No. | 851440-19-2 |
| Molecular Formula | C26H34FN3O6S |
| Molecular Weight | 535.63 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Rosuvastatin Impurity 206 (CAS 851440-19-2), a pharmacopoeial impurity reference standard (molecular formula C26H34FN3O6S, MW 535.63 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution, Rosuvastatin Impurity 206 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 535.63 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C26H34FN3O6S |
| Molecular Weight | 535.63 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Rosuvastatin Standards
- Rosuvastatin Impurity 156 (CAS CATO-C4X-1169156)
- Rosuvastatin Impurity 77 (CAS 615556-96-2)
- Rosuvastatin Impurity 184 (CAS CATO-C4X-1169184)
- Rosuvastatin Impurity 55 (CAS 289042-10-0)
- Rosuvastatin Impurity 124 (CAS 615263-60-0)
- Rosuvastatin Impurity 125 (CAS CATO-C4X-1169125)
- Rosuvastatin Impurity 126 (CAS CATO-C4X-1169126)
- Rosuvastatin Impurity 214 (CAS CATO-C4X-1169214)
Recommended Standards
- Thailanstatin (CAS 1426953-21-0)
- Orforglipron impurity 102 (CAS 3047292-99-6)
- PL 017 (CAS 83397-56-2)
- 9-((1R,3S)-3-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)cyclopentyl)-9H-purin-6-amine (CAS 1071906-30-3)
- Baricitinib Impurity 133 (CAS CATO-C4X-2260133)
- Imipenem Impurity 106 (CAS CATO-C4X-1662106)
- Vardenafil Impurity 29 (CAS 1009013-42-6)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com