N-[3-Chloro-4-[(3-fluorobenzyl)oxy]phenyl]-6-iodoquinazolin-4-amine Hydrochloride CAS 851684-46-3
| CAS No. | 851684-46-3 |
| Molecular Formula | C21H14ClFIN3O |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies N-[3-Chloro-4-[(3-fluorobenzyl)oxy]phenyl]-6-iodoquinazolin-4-amine Hydrochloride (CAS 851684-46-3), a certified reference material (molecular formula C21H14ClFIN3OHCl, MW 542.17 g/mol) for analytical method development and quality control.
N-[3-Chloro-4-[(3-fluorobenzyl)oxy]phenyl]-6-iodoquinazolin-4-amine Hydrochloride (C21H14ClFIN3OHCl) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine/iodine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H14ClFIN3O HCl |
| Molecular Weight | 542.17 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl/I-containing |
| Nitrogen Atoms | 3 |
Related N Standards
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Recommended Standards
- 3-(Boc-amino)-6,6-dichlorobicyclo[3.1.0]hexane-3-carboxylic Acid (CAS 1134759-39-9)
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- 2-(Aminomethyl)-4-bromo-6-(difluoromethyl)pyridine-3-acetonitrile (CAS 1805253-64-8)
- Ethyl 2-(2-ethylpyridin-4-yl)thiazole-4-carboxylate (CAS 630410-54-7)
- 3-(2,3-Dichlorophenyl)-2-methyl-1-propene (CAS 951892-49-2)
- Methyl 3-amino-3-(2,3-dichlorophenyl)propanoate (CAS 618109-83-4)
- Benzyl (6-(Hydrazinecarbonyl)pyridin-2-yl)carbamate (CAS 1262043-89-9)
- 4-Methoxy-3-((2-methylpiperidin-1-yl)methyl)benzaldehyde (CAS 1119450-98-4)
- N-(3,4-Dimethylphenyl)-2-((3-(2-hydroxyphenyl)-1H-1,2,4-triazol-5-yl)thio)acetamide (CAS 332126-74-6)
- Acetyl tetrapeptide-3 (CAS 827306-88-7)
Why CATO?
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