2-(Piperazin-1-yl)-n-[2-(trifluoromethyl)phenyl]acetamide CAS 851710-82-2
| CAS No. | 851710-82-2 |
| Molecular Formula | C13H16F3N3O |
| Molecular Weight | 287.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(Piperazin-1-yl)-n-[2-(trifluoromethyl)phenyl]acetamide.
CATO supplies 2-(Piperazin-1-yl)-n-[2-(trifluoromethyl)phenyl]acetamide (CAS 851710-82-2), a certified reference material (molecular formula C13H16F3N3O, MW 287.28 g/mol) for analytical method development and quality control.
The molecular framework of 2-(Piperazin-1-yl)-n-[2-(trifluoromethyl)phenyl]acetamide (C13H16F3N3O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-(Piperazin-1-yl)-n-[2-(trifluoromethyl)phenyl]acetamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H16F3N3O |
| Molecular Weight | 287.28 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Piperazin Standards
- 2-(3-Oxo-3-(piperazin-1-yl)propyl)isoindoline-1,3-dione (CAS 1018568-22-3)
- 1-(4-Phenyl-2-(piperazin-1-yl)thiazol-5-yl)ethan-1-one (CAS 1283108-94-0)
- 2-(4-Oxo-6-(piperazin-1-yl)quinazolin-3(4H)-yl)acetic acid (CAS 889958-08-1)
- 2-(((2-(Piperazin-1-yl)ethyl)amino)methylene)-1H-indene-1,3(2H)-dione (CAS 354543-33-2)
- Methyl 2-(piperazin-1-yl)-4-(trifluoromethyl)nicotinate (CAS 1221791-85-0)
- 2-(Piperazin-1-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine (CAS 1351990-53-8)
- 4-(Piperazin-1-ylsulfonyl)benzo[c][1,2,5]thiadiazole (CAS 488122-76-5)
- Methyl 4-(piperazin-1-ylsulfonyl)benzoate (CAS 919063-38-0)
Recommended Standards
- 1-[4-(4-Amino-2-trifluoromethylphenyl)piperazin-1-yl]ethanone (CAS 914348-88-2)
- 2,2,2-Trifluoro-1-(3-hydroxy-2,2,6-trimethyl-3,4-dihydroquinolin-1(2H)-yl)ethanone (CAS 828939-13-5)
- 1-[3-(4-Methylpiperazin-1-yl)-5-(trifluoromethyl)pyridin-2-yl]ethan-1-one (CAS 900014-77-9)
- 2,2,2-Trifluoro-N-(6-oxo-6-phenylhexyl)acetamide (CAS 39510-50-4)
- 1-(2-Cyclopropylpyrazolo[1,5-a]pyrazin-4-yl)pyrrolidin-3-amine (CAS 1713639-32-7)
- 6-Methoxy-5-nitroindoline (CAS 23772-40-9)
- 4-Iodo-3-methylbenzophenone (CAS 951887-39-1)
- Bis(4-diethylaminophenyl)methanol (CAS 134-91-8)
- Benzonitrile, 3-[(1S)-1-aminoethyl]- (CAS 127852-22-6)
- Ozanimod Impurity 28 (CAS CATO-C4X-29028)
- 1-(6-fluoro-2-naphthyl)ethanone (CAS 33627-02-0)
- 2-Fluoro-N-(1-hydroxypropyl)acetamide (CAS 60807-70-7)
- 1-(Benzo[d][1,3]dioxol-5-yl)-4,4,4-trifluorobutane-1,3-dione (CAS 306935-39-7)
- SV40 Nuclear Transport Signal Peptide Analog (CAS 104914-40-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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