(2,6-Dichloro-3-(hydroxymethyl)phenyl)boronic acid CAS 851756-55-3
| CAS No. | 851756-55-3 |
| Molecular Formula | C7H7BCl2O3 |
| Molecular Weight | 220.85 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies (2,6-Dichloro-3-(hydroxymethyl)phenyl)boronic acid (CAS 851756-55-3), a certified reference material (molecular formula C7H7BCl2O3, MW 220.85 g/mol) for analytical method development and quality control.
The molecular framework of (2,6-Dichloro-3-(hydroxymethyl)phenyl)boronic acid (C7H7BCl2O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), (2,6-Dichloro-3-(hydroxymethyl)phenyl)boronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H7BCl2O3 |
| Molecular Weight | 220.85 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
Related Dichloro Standards
- (2,3-Dichloro-4-methoxyphenyl)boronic acid (CAS 1190219-72-7)
- (2,4-Dichloro-6-methoxyphenyl)boronic acid (CAS 1221263-05-3)
- 4,5-Dichloro-2-methoxyphenylboronic acid (CAS 1256354-93-4)
- 2,5-Dichloro-4-methoxyphenylboronic acid (CAS 1612184-34-5)
- (3,5-Dichloro-4-methoxyphenyl)boronic acid (CAS 175883-61-1)
- (2,4-Dichloro-3-methoxyphenyl)boronic acid (CAS 944128-90-9)
- (2,4-Dichloro-5-methoxyphenyl)boronic acid (CAS 431942-67-5)
- (2,6-dichloro-3-methoxyphenyl)boronic acid (CAS 851756-57-5)
Recommended Standards
- (2,6-Dichloro-4-methoxyphenyl)boronic acid (CAS 851756-60-0)
- (3,4-Dichloro-2-methoxyphenyl)boronic acid (CAS 2096329-64-3)
- (3,6-Dichloro-2-methoxyphenyl)boronic acid (CAS 919355-31-0)
- 2,5-Dichloro-3-methoxyphenylboronic acid (CAS 919355-32-1)
- (E)-Doxepin (CAS 3607-34-9)
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- Semaglutide impurity 86 (CAS CATO-C4X-152686)
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