5-Amino-3-methylbenzo[d]isoxazole CAS 851768-35-9
| CAS No. | 851768-35-9 |
| Molecular Formula | C8H8N2O |
| Molecular Weight | 148.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-Amino-3-methylbenzo[d]isoxazole (CAS 851768-35-9), molecular formula C8H8N2O and molecular weight 148.16 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-Amino-3-methylbenzo[d]isoxazole (C8H8N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H8N2O |
| Molecular Weight | 148.16 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 2 |
Related Amino Standards
- 2-Amino-4-hydroxy-3-methylbenzonitrile (CAS 102569-26-6)
- 2-Amino-3-(2-aminoethoxy)propanoic acid (CAS 10367-17-6)
- 3-Amino-4-methylbenzisoxazole (CAS 1126636-46-1)
- 2-Amino-3-(hydroxymethyl)benzonitrile (CAS 114344-01-3)
- 2-Amino-7-methylbenzoxazole (CAS 1268154-07-9)
- 5-Amino-1H-indol-2-ol (CAS 1395493-23-8)
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- 2-Amino-6-methoxybenzonitrile (CAS 1591-37-3)
Recommended Standards
- 5-amino-2-methoxy-benzonitrile (CAS 214623-57-1)
- 5-Aminoindolin-2-one (CAS 20876-36-2)
- 5,8-Dihydroquinazolin-7(6H)-one (CAS 944895-94-7)
- 5-Aminoisoindolin-1-one (CAS 222036-66-0)
- 2-((5-Methoxy-1H-indol-3-yl)methylene)malononitrile (CAS 771574-78-8)
- 2-bromo-4-(sec-butyl)phenol 2-bromo-4-sec-butylphenol 63762-55-0 (CAS 63762-55-0)
- 3-Chloro-4-(2,4-dimethylphenoxy)aniline (CAS 937608-59-8)
- Methyl 4-(chlorosulfonyl)-6-methoxypicolinate (CAS 1393560-70-7)
- 6,6,6-Trifluorohexan-1-ol (CAS 65611-47-4)
- 4,4-Dimethyl-4H,6H,7H-pyrano[4,3-d][1,3]thiazol-2-amine (CAS 959749-31-6)
- 3-(3-Methylpiperazin-1-yl)pyrazine-2-carbonitrile hydrochloride (CAS 1384428-66-3)
- 2-Methyl-1H-benzo[d]imidazol-7-ol (CAS 94977-60-3)
- 5-Cyclopropoxy-2-methoxy-N-methylaniline (CAS 1243442-32-1)
- Semaglutide impurity 84 (CAS CATO-C4X-222684)
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