5-((3-Fluorophenyl)(4-methylpiperidin-1-yl)methyl)-2-methylthiazolo[3,2-b][1,2,4]triazol-6-ol CAS 851810-39-4
| CAS No. | 851810-39-4 |
| Molecular Formula | C18H21FN4OS |
| Molecular Weight | 360.45 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
5-((3-Fluorophenyl)(4-methylpiperidin-1-yl)methyl)-2-methylthiazolo[3,2-b][1,2,4]triazol-6-ol (CAS 851810-39-4) is a high-purity analytical reference standard with the molecular formula C18H21FN4OS and a molecular weight of 360.45 g/mol.
The molecular framework of 5-((3-Fluorophenyl)(4-methylpiperidin-1-yl)methyl)-2-methylthiazolo[3,2-b][1,2,4]triazol-6-ol (C18H21FN4OS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H21FN4OS |
| Molecular Weight | 360.45 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Fluorophenyl Standards
- 1-(4-Fluorophenyl)-3-(methylthio)-4,5-diphenyl-1H-pyrazole (CAS 871110-21-3)
- 1-(4-Fluorophenyl)-5-(methylthio)-3,4-diphenyl-1H-pyrazole (CAS 871110-09-7)
- 2-{[(3-fluorophenyl)methyl]sulfanyl}-4,5-diphenyl-1H-imidazole (CAS 339277-85-9)
- 5-((4-Fluorophenyl)(3-methylpiperidin-1-yl)methyl)-2-methylthiazolo[3,2-b][1,2,4]triazol-6-ol (CAS 851810-61-2)
- 4-[(4-Fluorophenyl)sulfanyl]-5-methanesulfonyl-2-phenylpyrimidine (CAS 339106-29-5)
- N-(2-fluorophenyl)-2-(5-methylthiophene-3-carboxamido)thiophene-3-carboxamide (CAS 717871-20-0)
- 3-[2-(4-Fluorophenyl)ethyl]-2,3,5,6,7,8-hexahydro-2-thioxo[1]benzothieno[2,3-d]pyrimidin-4(1H)-one (CAS 571155-96-9)
- 1-[4-(4-Fluorophenyl)piperazino]-3-(4-methoxyphenoxy)-2-propanol (CAS 439130-37-7)
Recommended Standards
- 4-Hydroxy-1-methyl-N-(4-methylphenyl)-2,2-dioxo-1,2-dihydro-2lambda~6~,1-benzothiazine-3-carbothioamide (CAS 477860-32-5)
- 4-Allyl-5-(2-(3,4-dimethoxyphenyl)thiazol-4-yl)-2,4-dihydro-3H-1,2,4-triazole-3-thione (CAS 400083-68-3)
- 6-Benzyl 1-tert-butyl hexahydro-1H-pyrrolo[2,3-c]pyridine-1,6(2H)-dicarboxylate (CAS 2079156-42-4)
- 4,4'-(Furan-2,5-diyl)bis(N-ethylbenzimidamide) (CAS 199919-01-2)
- 3,6,9,12-Tetraoxapentacosanoic acid, sodium salt (1:1) (CAS 117292-47-4)
- (1S,4s)-4-(trifluoromethoxy)cyclohexan-1-amine (CAS 2231664-77-8)
- 3-Cyclopropoxy-4-fluoro-5-iodopyridine (CAS 1243375-95-2)
- 4-(4-Chlorobenzyl)-4H-furo[3,2-b]pyrrole-5-carboxylic acid (CAS 1146291-70-4)
- 2-(Bromomethyl)-N,N-dimethylaniline (CAS 117426-12-7)
- Thieno[2,3-b]quinoxaline (CAS 54101-62-1)
- (2,3-Dihydrobenzofuran-5-yl)methanol (CAS 103262-35-7)
- N-(4-Methylbenzoyl)-3-(1H-pyrrol-1-yl)-2-thiophenecarbohydrazide (CAS 672925-24-5)
- 1,1-Dimethoxypentane-2,4-dione (CAS 55578-64-8)
- Peptide Impurity (CAS CATO-CPTD788810)
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