[(1S,3R)-1-Isopropyl-3-[[(3S,4S)-3-methoxytetrahydro-2H-pyran-4-yl]amino]cyclopentyl][3-(trifluoromethyl)-7,8-dihydro-1,6-naphthyridin-6(5H)-yl]methanone Succinate CAS 851916-42-2

Purity 97%+In StockPharmaceutical Standards
CAS No.851916-42-2
Molecular FormulaC24H34F3N3O3
Molecular WeightN/A
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

[(1S,3R)-1-Isopropyl-3-[[(3S,4S)-3-methoxytetrahydro-2H-pyran-4-yl]amino]cyclopentyl][3-(trifluoromethyl)-7,8-dihydro-1,6-naphthyridin-6(5H)-yl]methanone Succinate CAS 851916-42-2 chemical structure

Description

The occurrence of [(1S,3R)-1-Isopropyl-3-[[(3S,4S)-3-methoxytetrahydro-2H-pyran-4-yl]amino]cyclopentyl][3-(trifluoromethyl)-7,8-dihydro-1,6-naphthyridin-6(5H)-yl]methanone Succinate is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

[(1S,3R)-1-Isopropyl-3-[[(3S,4S)-3-methoxytetrahydro-2H-pyran-4-yl]amino]cyclopentyl][3-(trifluoromethyl)-7,8-dihydro-1,6-naphthyridin-6(5H)-yl]methanone Succinate (CAS 851916-42-2), molecular formula C24H34F3N3O3HCl and molecular weight 506.01 g/mol, is a CATO reference standard with documented purity and traceability.

[(1S,3R)-1-Isopropyl-3-[[(3S,4S)-3-methoxytetrahydro-2H-pyran-4-yl]amino]cyclopentyl][3-(trifluoromethyl)-7,8-dihydro-1,6-naphthyridin-6(5H)-yl]methanone Succinate (C24H34F3N3O3HCl) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), [(1S,3R)-1-Isopropyl-3-[[(3S,4S)-3-methoxytetrahydro-2H-pyran-4-yl]amino]cyclopentyl][3-(trifluoromethyl)-7,8-dihydro-1,6-naphthyridin-6(5H)-yl]methanone Succinate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC24H34F3N3O3 HCl
Molecular Weight506.01 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Halogen ContentF/Cl-containing
Nitrogen Atoms3

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