N-(1-Cyanocyclopentyl)-2-(4-(5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)acetamide CAS 851966-13-7
| CAS No. | 851966-13-7 |
| Molecular Formula | C18H22F3N5O |
| Molecular Weight | 381.40 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
N-(1-Cyanocyclopentyl)-2-(4-(5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)acetamide (CAS 851966-13-7) is a high-purity analytical reference standard with the molecular formula C18H22F3N5O and a molecular weight of 381.40 g/mol.
The molecular framework of N-(1-Cyanocyclopentyl)-2-(4-(5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)acetamide (C18H22F3N5O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), N-(1-Cyanocyclopentyl)-2-(4-(5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H22F3N5O |
| Molecular Weight | 381.40 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
Related N Standards
- 2-((1-Cyanocyclopentyl)amino)-2-oxoethyl 4-(furan-2-carboxamido)benzoate (CAS 871921-45-8)
- 2-((1-Cyanocyclopentyl)amino)-2-oxoethyl 3-bromo-4-methoxybenzoate (CAS 871304-95-9)
- N-(1-Cyanocyclopentyl)-2-((5,7-dichloro-2-methylquinolin-8-yl)oxy)acetamide (CAS 1013724-34-9)
- N-(1-Cyanocyclopentyl)-2-((5-((2,3-dimethylphenyl)amino)-1,3,4-thiadiazol-2-yl)thio)acetamide (CAS 863414-15-7)
- N-(1-Cyanocyclopentyl)-2-((5-((4-ethylphenyl)amino)-1,3,4-thiadiazol-2-yl)thio)acetamide (CAS 863420-46-6)
- N-(1-Cyanocyclopentyl)-2-((5-(m-tolylamino)-1,3,4-thiadiazol-2-yl)thio)acetamide (CAS 863417-78-1)
- N-(1-Cyanocyclopentyl)-2-((5-(o-tolylamino)-1,3,4-thiadiazol-2-yl)thio)acetamide (CAS 863412-31-1)
- N-(1-Cyanocyclopentyl)-2-((5-(p-tolylamino)-1,3,4-thiadiazol-2-yl)thio)acetamide (CAS 863415-50-3)
Recommended Standards
- Methyl (4-(8-fluoro-1-oxo-2,3,4,6-tetrahydro-1H-azepino[5,4,3-cd]indol-5-yl)benzyl)(methyl)carbamate (CAS 880160-69-0)
- N-(β-D-Glucopyranosyl)-N2-acetyl-S-nitroso-D,L-penicillamide (CAS 214193-25-6)
- Fructose-1-S-nitroso-N-acetyl-D,L-penicillamine (CAS 330688-79-4)
- Uridine, 2',5'-dideoxy-5'-[[(4-methylphenyl)sulfonyl]amino]- (CAS 864948-91-4)
- tert-butyl N-(1,2,3,4-tetrahydroisoquinolin-8-yl)carbamate (CAS 1540071-42-8)
- Ethyl Bromoacetate- (CAS 61898-49-5)
- 2-Amino-4-(trifluoromethyl)nicotinaldehyde (CAS 1227582-11-7)
- Methyl 6-oxo-5-azaspiro[2.4]heptane-4-carboxylate (CAS 1779454-83-9)
- tert-butyl 4-(2-iodoethyl)piperidine-1-carboxylate (CAS 89151-46-2)
- 6,6'-Dimethyl 5,5'-dibromo-2H,2'H,3H,3'H-[1,1'-biindole]-6,6'-dicarboxylate (CAS 2007910-50-9)
- Ethyl 2-(3-Methyl-1,2,4-oxadiazol-5-yl)acetate (CAS 1216294-40-4)
- (5-(1-Cyanocyclopropyl)-2-fluorophenyl)boronic acid (CAS 1256345-50-2)
- 3-Chloro-2-hydrazinopyridine (CAS 22841-92-5)
- Tau Peptide (304-318) trifluoroacetate salt (CAS 330456-49-0)
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