7-Fluoro-6-methoxyquinolin-3-amine CAS 851973-13-2
| CAS No. | 851973-13-2 |
| Molecular Formula | C10H9FN2O |
| Molecular Weight | 192.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 192.19 g/mol gives 7-Fluoro-6-methoxyquinolin-3-amine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
7-Fluoro-6-methoxyquinolin-3-amine (CAS 851973-13-2) is a high-purity analytical reference standard with the molecular formula C10H9FN2O and a molecular weight of 192.19 g/mol.
The molecular framework of 7-Fluoro-6-methoxyquinolin-3-amine (C10H9FN2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 7-Fluoro-6-methoxyquinolin-3-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H9FN2O |
| Molecular Weight | 192.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
- 7-Fluoro-2-methoxy-8-methylquinoxaline (CAS 952587-08-5)
- 7-Fluorospiro[2,3-dihydro-2,6-naphthyridine-4,1'-cyclopropane]-1-one (CAS 2854319-53-0)
- 6-(4-Fluorophenyl)-2,3,4,5-tetrahydropyridazin-3-one (CAS 39499-62-2)
- 8-Fluoro-6-methoxyquinolin-3-amine (CAS 851973-19-8)
- n-(P-tolyl)bicyclo[2.2.1]heptan-2-amine (CAS 912552-69-3)
- 5-(Difluoromethoxy)-2-methoxybenzonitrile (CAS 1261438-86-1)
- 2-(Benzo[e][1,2,4]triazin-3-yl)acetic acid (CAS 77475-33-3)
- tert-Butyl 2-(2-aminopyridin-3-yl)pyrrolidine-1-carboxylate (CAS 1352482-60-0)
- 2-Amino-N-cyclopropylacetamide (CAS 120436-02-4)
- 2-Propenoic acid, 2-methyl-, methyl ester, polymer with butyl 2-propenoate and 2-methyl-2-propenamide (CAS 26715-67-3)
- 5,7-Dihydroxy-3,4-dimethyl-2H-chromen-2-one (CAS 103986-39-6)
- (+)-Menthofuran (CAS 17957-94-7)
- tert-butyl (2S)-2-(p-tolylsulfonyloxymethyl)azetidine-1-carboxylate (CAS 209328-53-0)
- Uremic Pentapeptide (CAS 71494-20-7)
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