4-Chloro-6-fluoro-7-methoxyquinoline CAS 851985-92-7
| CAS No. | 851985-92-7 |
| Molecular Formula | C10H7ClFNO |
| Molecular Weight | 211.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
4-Chloro-6-fluoro-7-methoxyquinoline (CAS 851985-92-7), molecular formula C10H7ClFNO and molecular weight 211.62 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C10H7ClFNO, 4-Chloro-6-fluoro-7-methoxyquinoline contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 211.62 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H7ClFNO |
| Molecular Weight | 211.62 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
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- (2-Chloro-6-fluoroquinolin-3-yl)methanol (CAS 1017403-67-6)
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Recommended Standards
- 4-Chloro-3-fluoro-7-methoxyquinoline (CAS 852062-11-4)
- 4-Chloro-7-fluoro-6-methoxyquinoline (CAS 25759-94-8)
- 4-(Difluoromethyl)-2-Methyl-1,3-Thiazole-5-Carbonyl Chloride (CAS 203448-82-2)
- 5-(2-Chloro-6-fluoro-3-methylphenyl)oxazole (CAS 2364585-07-7)
- 6,8-Difluoro-2h-chromene (CAS 1015938-81-4)
- 3,4-Dibromo-6-ethoxy-2-(hydroxymethyl)phenol (CAS 35090-69-8)
- 5,5'-(Dimethylsilanediyl)diisophthalic acid (CAS 1171890-34-8)
- n-(Thiazol-2-ylmethyl)ethanamine (CAS 680591-00-8)
- 3-Amino-1-(3-(trifluoromethyl)benzyl)piperidin-2-one (CAS 1404945-84-1)
- 4-Bromo-3-nitrobenzoyl chloride (CAS 335015-51-5)
- Urapidil Impurity 83 (CAS CATO-C4X-192483)
- 3-(Aminooxy)benzonitrile (CAS 197588-20-8)
- 3-Methyl-N-(3-methylphenyl)-[1,2,4]triazolo-[4,3-a]pyridine-8-sulfonamide (CAS 1291487-11-0)
- Peptide Impurity 70 TFA Salt (CAS CATO-CPTD788570)
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