2-Bromo-1-methyl-1H-imidazole-4-carboxylic Acid CAS 852181-03-4
| CAS No. | 852181-03-4 |
| Molecular Formula | C5H5BrN2O2 |
| Molecular Weight | 205.01 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
2-Bromo-1-methyl-1H-imidazole-4-carboxylic Acid (CAS 852181-03-4), molecular formula C5H5BrN2O2 and molecular weight 205.01 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 2-Bromo-1-methyl-1H-imidazole-4-carboxylic Acid (C5H5BrN2O2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 205.01 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C5H5BrN2O2 |
| Molecular Weight | 205.01 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Bromo Standards
- 4-Bromo-1-methyl-1H-imidazole-2-carboxylic acid (CAS 1027134-70-8)
- 5-Bromo-2-methyl-1H-imidazole-4-carboxylic acid (CAS 1093261-50-7)
- 5-Bromo-1-methyl-1,4-dihydropyrazine-2,3-dione (CAS 1133433-93-8)
- 5-Bromo-3-hydroxy-1-methylpyrazin-2(1H)-one (CAS 1133573-50-8)
- 5-bromo-4-methyl-1H-imidazole-2-carboxylic acid (CAS 1171125-21-5)
- 2-(4-Bromo-1H-imidazol-1-yl)acetic acid (CAS 1211524-53-6)
- 5-Bromo-N-methyl-1H-1,2,4-triazole-3-carboxamide (CAS 1232793-93-9)
- Methyl 5-bromo-1H-pyrazole-3-carboxylate (CAS 1328893-17-9)
Recommended Standards
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