2-Chloro-N-[3-cyano-1-(furan-2-ylmethyl)-4,5-dimethyl-1h-pyrrol-2-yl]acetamide CAS 852217-67-5
| CAS No. | 852217-67-5 |
| Molecular Formula | C14H14ClN3O2 |
| Molecular Weight | 291.73 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Chloro-N-[3-cyano-1-(furan-2-ylmethyl)-4,5-dimethyl-1h-pyrrol-2-yl]acetamide.
CATO supplies 2-Chloro-N-[3-cyano-1-(furan-2-ylmethyl)-4,5-dimethyl-1h-pyrrol-2-yl]acetamide (CAS 852217-67-5), a certified reference material (molecular formula C14H14ClN3O2, MW 291.73 g/mol) for analytical method development and quality control.
The molecular framework of 2-Chloro-N-[3-cyano-1-(furan-2-ylmethyl)-4,5-dimethyl-1h-pyrrol-2-yl]acetamide (C14H14ClN3O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H14ClN3O2 |
| Molecular Weight | 291.73 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
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Recommended Standards
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- 2-[2-Chloro-4-(hydroxymethyl)phenoxy]-n-phenylacetamide (CAS 693820-35-8)
- 3-Chloro-5,6-diphenylpyridazine-4-carbonitrile (CAS 94011-79-7)
- 1-(1-Methyl-1h-indol-3-yl)ethan-1-amine (CAS 52971-31-0)
- Methyl 1-(2-bromo-4-formylphenoxy)cyclopropanecarboxylate (CAS 1399653-64-5)
- 2-Amino-N-((3-isopropyl-1,2,4-oxadiazol-5-yl)methyl)acetamide hydrochloride (CAS 1435804-45-7)
- 4-(3,4-dichlorophenyl)piperazinyl phenylcyclopentyl ketone (CAS 1024360-29-9)
- Mirogabalin Impurity 36 (CAS CATO-C4X-292436)
- 5-Bromo-2-phenylpyrimidine-4-carboxylic acid (CAS 179260-95-8)
- (E)-1-(3-chloroprop-1-en-1-yl)-3-methoxybenzene (CAS 478930-89-1)
- 2-(Benzo[d]oxazol-2-yl)-3-hydroxyacrylaldehyde (CAS 39116-24-0)
- Ethyl 5,7-dichloroimidazo[1,2-c]pyrimidine-2-carboxylate (CAS 1289151-91-2)
- Glucagon receptor antagonist I (CAS 438618-32-7)
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