Tert-butyl (3R,4S)-3-hydroxy-4-(hydroxymethyl)piperidine-1-carboxylate CAS 852358-78-2
| CAS No. | 852358-78-2 |
| Molecular Formula | C11H21NO4 |
| Molecular Weight | 231.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Tert-butyl (3R,4S)-3-hydroxy-4-(hydroxymethyl)piperidine-1-carboxylate (CAS 852358-78-2) is a high-purity analytical reference standard with the molecular formula C11H21NO4 and a molecular weight of 231.29 g/mol.
The molecular framework of Tert-butyl (3R,4S)-3-hydroxy-4-(hydroxymethyl)piperidine-1-carboxylate (C11H21NO4) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Tert-butyl (3R,4S)-3-hydroxy-4-(hydroxymethyl)piperidine-1-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H21NO4 |
| Molecular Weight | 231.29 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 1 |
Recommended Standards
- Tert-butyl (3R,4S)-3,4-dimethoxypyrrolidine-1-carboxylate (CAS 2368911-31-1)
- tert-Butyl (3R,6R)-3,6-dihydroxyazepane-1-carboxylate (CAS 2791276-93-0)
- tert-Butyl (3R,4R)-4-hydroxy-3-methoxypiperidine-1-carboxylate (CAS 2382396-70-3)
- tert-Butyl (3S)-3-(2-hydroxyethyl)morpholine-4-carboxylate (CAS 813433-76-0)
- 3-Phenyl-5,6-dihydro-4H-cyclopenta[d]isoxazole (CAS 13243-54-4)
- (1S,2R)-2-methoxycyclopentane-1-carboxylic acid (CAS 1403894-04-1)
- 3-(4-Bromothiophen-2-yl)propiolic acid (CAS 1403564-62-4)
- Tetrasodium pyrophosphate (CAS 7722-88-5)
- 5,7-Dihydro-4H-purin-6-amine (CAS 866231-41-6)
- (2s,3s)-2-(9h-Fluoren-9-ylmethoxycarbonylamino)-3-(2-naphthyl)butanoicacid (CAS 208582-08-5)
- (3-(2-Formylphenoxy)-2-hydroxypropyl)triphenylphosphonium bromide (CAS 16315-64-3)
- 5-Bromo-2-isopropoxy-3-methoxypyridine (CAS 1241752-33-9)
- Ethyl 3-amino-3-(pyridin-4-yl)butanoate (CAS 1536216-77-9)
- D-Ile12-Tirzepatide (CAS CATO-CPTD788921)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com