1-(2,3-Dihydro-1H-pyrrol-1-yl)-2,2,2-trifluoroethanone CAS 85236-73-3
| CAS No. | 85236-73-3 |
| Molecular Formula | C6H6F3NO |
| Molecular Weight | 165.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
1-(2,3-Dihydro-1H-pyrrol-1-yl)-2,2,2-trifluoroethanone (CAS 85236-73-3), molecular formula C6H6F3NO and molecular weight 165.11 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 1-(2,3-Dihydro-1H-pyrrol-1-yl)-2,2,2-trifluoroethanone is typically white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 165.11 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H6F3NO |
| Molecular Weight | 165.11 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1981 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Dihydro Standards
- 1,2-Dihydro-5-nitro-2-oxo-3-pyridinecarbonitrile (CAS 31309-38-3)
- 3-Oxo-2,3-dihydro-1H-pyrrolizine-5-carboxylic acid (CAS 132114-55-7)
- 2,3-Dihydro-[1,4]dioxino-[2,3-c]pyridine-5-carbaldehyde (CAS 1414864-13-3)
- 6,7-Dihydro-5H-pyrrolo[2,3-d]pyrimidine-4-carboxylic acid (CAS 1513237-82-5)
- 2,3-Dihydro-5-nitrobenzofuran (CAS 17403-47-3)
- 1-Oxo-2,3-dihydro-1H-pyrrolizine-3-carboxylic acid (CAS 716362-06-0)
- 2,3-Dihydro-[1,4]dioxino[2,3-b]pyridine-6-carbaldehyde (CAS 615568-24-6)
- 2,3-Dihydro[1,4]dioxino[2,3-c]pyridine-7-carbaldehyde (CAS 443955-90-6)
Recommended Standards
- (S)-2,2,2-Trifluoro-1-(furan-2-yl)ethan-1-amine (CAS 413621-62-2)
- (R)-2,2,2-trifluoro-1-(furan-2-yl)ethan-1-amine (CAS 764641-05-6)
- 2,2,2-Trifluoro-1-(furan-2-yl)ethanamine (CAS 65686-90-0)
- (5-(Trifluoromethyl)furan-2-yl)methanamine (CAS 868755-68-4)
- 6,6-diethyl-4,5,6,7-tetrahydro-1,3-benzothiazol-2-amine hydrobromide (CAS 1909305-05-0)
- 1-(Benzyloxy)-3-bromopropan-2-one (CAS 144318-33-2)
- Ethyl 2-(4-(2,6-difluorophenyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)acetate (CAS 861206-30-6)
- 2-(3-(Cyclopropylcarbamoyl)-6-oxo-5,6-dihydropyridazin-1(4H)-yl)acetic acid (CAS 1708268-24-9)
- 2-Chlorophenethyl Bromide (CAS 16793-91-2)
- (2'-Fluoro[1,1'-biphenyl]-4-yl)acetonitrile (CAS 893737-72-9)
- [4-(phenylsulfanyl)phenyl]methanamine (CAS 84212-05-5)
- Semaglutide (CAS 910463-68-2)
- 4-((1H-1,2,4-Triazol-1-yl)methyl)benzoic acid (CAS 160388-54-5)
- Semaglutide impurity 63 (CAS CATO-C4X-222663)
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