Ethyl 4-((3-(4-fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)thio)-3-oxobutanoate CAS 852374-39-1
| CAS No. | 852374-39-1 |
| Molecular Formula | C17H15FN4O3S |
| Molecular Weight | 374.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Ethyl 4-((3-(4-fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)thio)-3-oxobutanoate is closely related to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Ethyl 4-((3-(4-fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)thio)-3-oxobutanoate (CAS 852374-39-1), molecular formula C17H15FN4O3S and molecular weight 374.39 g/mol, is a CATO reference standard with documented purity and traceability.
Ethyl 4-((3-(4-fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)thio)-3-oxobutanoate (C17H15FN4O3S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Ethyl 4-((3-(4-fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)thio)-3-oxobutanoate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H15FN4O3S |
| Molecular Weight | 374.39 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Ethyl Standards
- 2-[4-(2-Fluorophenyl)-1,3-thiazol-2-yl]-3-(4-oxo-4H-chromen-3-yl)acrylonitrile (CAS 861211-44-1)
- Ethyl 4-((3-(3-fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)thio)-3-oxobutanoate (CAS 852375-24-7)
- 7-(4-Fluorophenyl)-2-(4-phenylpiperazin-1-yl)-[1,2,4]triazolo[1,5-a]pyrimidine (CAS 338403-72-8)
- (5-((4-Fluorophenyl)thio)-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methyl cyclopropanecarboxylate (CAS 955966-46-8)
- N-(4-fluorophenyl)-3-tosyl-3-azabicyclo[3.1.0]Hexane-2-carboxamide (CAS 1101135-83-4)
- 2-(4-((4-Fluorophenyl)sulfonyl)piperazin-1-yl)-4,6-dimethylnicotinonitrile (CAS 478081-73-1)
- 5-((4-Fluorophenyl)thio)-1,3-diphenyl-1H-pyrazole-4-carbaldehyde (CAS 955964-28-0)
- 5-(4-Fluorophenyl)-7-(pentafluoroethyl)pyrazolo-[1,5-a]pyrimidine-2-carboxylic acid (CAS 676521-71-4)
Recommended Standards
- Ethyl 5-cyano-6-(2-methoxyphenoxy)-2-phenylpyridine-3-carboxylate (CAS 306980-19-8)
- Rebamipide impurity 01 (CAS 4900-38-3)
- Ethyl 5-formyl-2-((5-formyl-4-methyl-3-(propionyloxy)-1H-pyrrol-2-yl)methyl)-4-methyl-1H-pyrrole-3-carboxylate (CAS 6339-67-9)
- Boc-NH-PEG2-C2-NHS ester (CAS 2183440-73-3)
- 4-Bromopyrimidin-2-yl acetate (CAS 1209458-50-3)
- 2,2-Dimethyl-2,3,7,7a-tetrahydroimidazo[5,1-b]thiazole-3,7-dicarboxylic acid (CAS 3053-88-1)
- Cyclobutyl 2,4-difluorophenyl ketone (CAS 898791-26-9)
- 1-(2-Methyl-4-propoxyphenyl)ethan-1-one (CAS 875818-96-5)
- tert-Butyl 2-(p-tolyl)acetate (CAS 33155-60-1)
- tert-Butyl 4-(2-mercaptoethyl)piperidine-1-carboxylate (CAS 1420841-79-7)
- 4-(2-(4-Nitrophenoxy)acetamido)benzene-1-sulfonyl fluoride (CAS 21315-95-7)
- 1-Bromo-3-butoxy-5-nitrobenzene (CAS 1881321-83-0)
- 4-Methyl-1,3-dioxane (CAS 1120-97-4)
- 69558-55-0 O3Y80ZF13F Thymopentin Thymopentin [USAN:INN:BAN] L-Tyrosine, N-(N-(N-(N2-L-arginyl-L-lysyl)-L-alpha-aspartyl)-L-valyl)- L-Tyrosine, N-(N-(N-(N(sup 2)-L-arginyl-L-lysyl)-L-alpha-aspartyl)-L-valyl)- Thymopentine [French] Thymopentinum [Latin] Timopentina [Spanish] Thymopoietin 32-36 TP-5 Thymopoietin pentapeptide ORF-15244 Thymopentine Thymopentinum Timopentina ORF 15244 UNII-O3Y80ZF13F (CAS 69558-55-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com