2-Chloro-1-[1-(ethanesulfonyl)-2,3-dihydro-1h-indol-5-yl]ethan-1-one CAS 852399-95-2
| CAS No. | 852399-95-2 |
| Molecular Formula | C12H14ClNO3S |
| Molecular Weight | 287.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Chloro-1-[1-(ethanesulfonyl)-2,3-dihydro-1h-indol-5-yl]ethan-1-one.
2-Chloro-1-[1-(ethanesulfonyl)-2,3-dihydro-1h-indol-5-yl]ethan-1-one (CAS 852399-95-2), molecular formula C12H14ClNO3S and molecular weight 287.76 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-Chloro-1-[1-(ethanesulfonyl)-2,3-dihydro-1h-indol-5-yl]ethan-1-one (C12H14ClNO3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-Chloro-1-[1-(ethanesulfonyl)-2,3-dihydro-1h-indol-5-yl]ethan-1-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H14ClNO3S |
| Molecular Weight | 287.76 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 2-(5-Chloro-2-ethoxy-phenyl)-thiazolidine-4-carboxylic acid (CAS 1033301-31-3)
- 2-Chloro-1-(1-methanesulfonyl-1,2,3,4-tetrahydroquinolin-6-yl)ethan-1-one (CAS 851721-90-9)
- 2-chloro-1-[2-methyl-1-(methylsulfonyl)-2,3-dihydro-1H-indol-5-yl]ethanone (CAS 852388-73-9)
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- Methyl (3-chloro-4-dimethylthiocarbamoyloxyphenyl)-acetate (CAS 91373-91-0)
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Recommended Standards
- 2-[(4-chlorophenyl)formamido]-4-(methylsulfanyl)butanoic acid (CAS 69605-01-2)
- 2-[(2-chlorophenyl)formamido]-4-(methylsulfanyl)butanoic acid (CAS 65054-72-0)
- 3-(((4-Chlorophenyl)imino)methyl)benzo[c]thiophen-1-ol (CAS 338954-45-3)
- 2,4-Dimethyl-3-(2-oxopyrrolidin-1-yl)benzenesulfonyl chloride (CAS 331256-61-2)
- 5-Fluoro-1-(triisopropylsilyl)-1h-pyrrolo[2,3-b]pyridine-4-carbonitrile (CAS 1228666-58-7)
- 4-Chloro-7-methylquinazoline (CAS 90272-83-6)
- 3,5-Di(9H-carbazol-9-yl)aniline (CAS 1384449-05-1)
- 3-(4-Bromophenyl)-7-methoxy-4-methyl-2H-chromen-2-one (CAS 262591-03-7)
- 5-[(2-Methoxyethyl)thio]-1,3,4-thiadiazol-2-amine (CAS 82381-77-9)
- (4E)-3-Phenyl-4-{[(thiophen-2-ylmethyl)amino]methylidene}-4,5-dihydro-1H-pyrazol-5-one (CAS 240116-00-1)
- 1-(2-Chlorobenzoyl)piperidin-4-one (CAS 1016700-87-0)
- 5-Amino-3,3-dimethyl-1,3-dihydro-2H-indol-2-one hydrochloride (CAS 1401425-29-3)
- 2-(1H-benzo[d]imidazol-2-yl)benzonitrile (CAS 76889-76-4)
- Semaglutide Impurity 16 (CAS CATO-C4X-222616)
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