2-Chloro-6-methoxy-3-phenylquinoline CAS 85274-57-3
| CAS No. | 85274-57-3 |
| Molecular Formula | C16H12ClNO |
| Molecular Weight | 269.73 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Chloro-6-methoxy-3-phenylquinoline (CAS 85274-57-3), molecular formula C16H12ClNO and molecular weight 269.73 g/mol, is a CATO reference standard with documented purity and traceability.
2-Chloro-6-methoxy-3-phenylquinoline (C16H12ClNO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H12ClNO |
| Molecular Weight | 269.73 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1981 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 4-benzyl-3-chloro-5-phenyl-4H-1,2,4-triazole (CAS 1020043-28-0)
- 6-Chloro-8-methyl-3-phenylquinolin-2-ol (CAS 1031928-31-0)
- 5-Chloro-8-methyl-2-phenylquinolin-4-ol (CAS 1070879-82-1)
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Recommended Standards
- 2-Chloro-5-methanesulfonylbenzene-1-sulfonamide (CAS 3544-47-6)
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- 2-Chloro-N-(2-morpholinoethyl)nicotinamide (CAS 551901-48-5)
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