Cabergoline EP Impurity D CAS 85329-86-8
| CAS No. | 85329-86-8 |
| Molecular Formula | C23H32N4O |
| Molecular Weight | 380.53 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, Cabergoline EP Impurity D is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 380.53 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, Cabergoline EP Impurity D (CAS 85329-86-8, C23H32N4O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H32N4O |
| Molecular Weight | 380.53 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1981 |
| Nitrogen Atoms | 4 |
Related Cabergoline Standards
- Cabergoline Impurity 7 (CAS CATO-C4X-27747)
- Cabergoline Impurity 13 (CAS CATO-C4X-277413)
- Cabergoline Impurity 12 (CAS CATO-C4X-277412)
- Cabergoline Impurity 10 (CAS 1380085-95-9)
- Cabergoline Impurity 2 (CAS 856676-33-0)
- Cabergoline EP Impurity B (CAS 166533-36-4)
- Cabergoline Impurity 5 (CAS 81409-91-8)
- Cabergoline (CAS 81409-90-7)
Recommended Standards
- Benzydamine Hydrochloride EP Impurity D (CAS 1337966-15-0)
- 3-[6-(Dimethylamino)-4-methyl-3-pyridinyl]-2,5-dimethyl-N,N-dipropylpyrazolo[1,5-a]pyrimidin-7-amine (CAS 195055-03-9)
- 17-epi Limaprost (CAS CATO-C4X-21454)
- Boc-Met-Met-OH (CAS 51529-24-9)
- Relugolix Impurity 180 (CAS CATO-C4X-2429180)
- Atracurium Besilate EP Impurity I (CAS CATO-C4X-185058)
- Alogliptin impurity 88 (CAS 1473368-47-6)
- 2-(3,5-Dimethyl-1H-pyrazol-1-yl)-4,7-dimethylbenzo[d]thiazole (CAS 1147196-34-6)
- 1-(2-Cyclopropylethyl)-3-(1,1-dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)-6-fluoro-4-hydroxyquinolin-2(1H)-one (CAS 477931-14-9)
- (R)-3,3-difluoro-4-methoxypiperidine (CAS 2306252-78-6)
- 3-(5,6,7,8-Tetrahydronaphthalen-2-yl)propanoic acid (CAS 13019-12-0)
- 1,8-Dihydroxy-3-methyl-2-phenethylanthracene-9,10-dione (CAS 62955-02-6)
- 1-(2,2-Diethoxyethyl)-4-methylpiperazine (CAS 1343344-74-0)
- C-Type Natriuretic Peptide (32-53) (human, porcine, rat) (CAS 127869-51-6)
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