Ethyl 7-(tert-butyl)-3-(4-fluorobenzoyl)indolizine-1-carboxylate CAS 853329-58-5
| CAS No. | 853329-58-5 |
| Molecular Formula | C22H22FNO3 |
| Molecular Weight | 367.41 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Ethyl 7-(tert-butyl)-3-(4-fluorobenzoyl)indolizine-1-carboxylate (CAS 853329-58-5), molecular formula C22H22FNO3 and molecular weight 367.41 g/mol, is a CATO reference standard with documented purity and traceability.
Ethyl 7-(tert-butyl)-3-(4-fluorobenzoyl)indolizine-1-carboxylate (C22H22FNO3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures Ethyl 7-(tert-butyl)-3-(4-fluorobenzoyl)indolizine-1-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H22FNO3 |
| Molecular Weight | 367.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- 2-Amino-4-piperazino-6-(3,4-dimethoxyphenyl)pteridine (CAS 278800-16-1)
- N-(2-(furan-2-yl)-6-(1H-pyrazol-1-yl)pyrimidin-4-yl)-2-(4-methylpiperazin-1-yl)acetamide (CAS 912935-90-1)
- Methyl 4-(((tert-butoxycarbonyl)amino)methyl)-6-fluoro-2,2-dimethylchroman-8-carboxylate (CAS 1956380-93-0)
- N-{1-({2-[(Dimethylamino)methylene]hydrazino}carbonyl)-2-[(4-methyl-2-pyrimidinyl)amino]vinyl}benzenecarboxamide (CAS 339010-35-4)
- Tert-butyl 4-(5-hydroxypyrimidin-2-yl)piperidine-1-carboxylate (CAS 1379522-56-1)
- Ticagrelor Impurity 72 (CAS 63755-08-8)
- (R)-1-(6-Chloropyridin-3-yl)ethan-1-amine hydrochloride (CAS 1391444-87-3)
- 2-(tert-Butyl)-4-cyclopropoxy-1-(trifluoromethyl)benzene (CAS 1243369-88-1)
- 1-(4-Ethoxyphenyl)-N-methylethan-1-amine hydrochloride (CAS 1269099-42-4)
- Methyl 2-amino-5-(4-chlorophenoxy)benzoate (CAS 1291530-09-0)
- 8-(Bicyclo[2.2.1]heptan-2-ylamino)-7-chloroquinoline-5,6-dione (CAS 25943-52-6)
- (S)-Methyl 2-(1-aminoethyl)-5-iodobenzoate (CAS 1217644-98-8)
- 6-Hexyloxy-3,4-dihydro-2H-naphthalen-1-one (CAS 62324-94-1)
- Glucagon (19-29) (human, rat, porcine) (CAS 64790-15-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com