5-(2-Chlorophenyl)-N-(2,4-difluorophenyl)furan-2-carboxamide CAS 853331-40-5
| CAS No. | 853331-40-5 |
| Molecular Formula | C17H10ClF2NO2 |
| Molecular Weight | 333.72 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 333.72 g/mol gives 5-(2-Chlorophenyl)-N-(2,4-difluorophenyl)furan-2-carboxamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
5-(2-Chlorophenyl)-N-(2,4-difluorophenyl)furan-2-carboxamide (CAS 853331-40-5), molecular formula C17H10ClF2NO2 and molecular weight 333.72 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 5-(2-Chlorophenyl)-N-(2,4-difluorophenyl)furan-2-carboxamide (C17H10ClF2NO2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 333.72 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H10ClF2NO2 |
| Molecular Weight | 333.72 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chlorophenyl Standards
- (4-Chlorophenyl)methyl N-[1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]carbamate (CAS 320423-05-0)
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- 4-((4-Chlorophenyl)thio)-N-ethyl-6-(trifluoromethyl)pyrimidin-2-amine (CAS 339010-87-6)
- 4-[(4-Chlorophenyl)sulfanyl]-N,N-dimethyl-6-(trifluoromethyl)pyrimidin-2-amine (CAS 338792-24-8)
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Recommended Standards
- 2-[3-({[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanyl}methyl)-1H-1,2,4-triazol-5-yl]acetonitrile (CAS 306976-87-4)
- Methyl 7-chloro-2-(methoxymethyl)-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylate (CAS 338778-39-5)
- 1-(3-Chloro-2-hydroxypropyl)-3,5-bis(oxiranylmethyl)-1,3.5-triazine-2,4,6(1H,3H,5H)-trione (CAS 78627-42-6)
- Methyl Octadecanoate-d35 (CAS 29823-25-4)
- 3H-Dinaphth[2,1-c:1′,2′-e]azepine, 4,4′-(1R,2R)-1,2-cyclohexanediylbis[4,5-dihydro-, (11bR,11′bR)- (CAS 524941-65-9)
- 1250099-01-4 6-(5-Amino-1H-1,2,4-triazol-3-yl)cyclohex-3-ene-1-carboxylic acid MFCD14630862 (CAS 1250099-01-4)
- 1-Methyl-2-oxopiperidine-4-carbonyl chloride (CAS 1858257-21-2)
- n-Cyclopropyl-2-(3-(trifluoromethyl)-1h-pyrazol-1-yl)acetamide (CAS 1281014-72-9)
- 2,3,4-Trichloro-5-fluorobenzoic acid (CAS 115549-04-7)
- Ethyl 2-amino-3-{[3-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)propyl]sulfanyl}propanoate; trifluoroacetic acid (CAS 1078611-34-3)
- 3-(2-Fluorophenyl)-6-phenylisoxazolo[5,4-b]pyridine-4-carboxylic acid (CAS 1018143-92-4)
- (2-(4-Methoxyphenyl)-1H-imidazol-5-yl)methanamine (CAS 944903-56-4)
- tert-Butyl (N-methylsulfamoyl)carbamate (CAS 125987-94-2)
- Semaglutide impurity 86 (CAS CATO-C4X-222686)
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