Tert-butyl 4-(hydroxymethyl)-4-(pyridin-2-yl)piperidine-1-carboxylate CAS 853576-51-9
| CAS No. | 853576-51-9 |
| Molecular Formula | C16H24N2O3 |
| Molecular Weight | 292.37 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Tert-butyl 4-(hydroxymethyl)-4-(pyridin-2-yl)piperidine-1-carboxylate (CAS 853576-51-9), molecular formula C16H24N2O3 and molecular weight 292.37 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Tert-butyl 4-(hydroxymethyl)-4-(pyridin-2-yl)piperidine-1-carboxylate (C16H24N2O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Tert-butyl 4-(hydroxymethyl)-4-(pyridin-2-yl)piperidine-1-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H24N2O3 |
| Molecular Weight | 292.37 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 2 |
Recommended Standards
- tert-Butyl 4-(hydroxy(pyridin-2-yl)methyl)piperidine-1-carboxylate (CAS 333986-05-3)
- tert-Butyl 4-(hydroxymethyl)-4-(pyridin-4-yl)piperidine-1-carboxylate (CAS 954125-20-3)
- tert-Butyl 4-(4-hydroxybenzyl)piperazine-1-carboxylate (CAS 77278-44-5)
- tert-Butyl 7-(1-hydroxypropan-2-yl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxylate (CAS 959992-13-3)
- (E)-{1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethylidene}[(4-chlorophenyl)methoxy]amine (CAS 866132-27-6)
- 2,4-Dichloro-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine hydrochloride(1:x) (CAS 635698-30-5)
- 6-Pentafluoroethyl-5-trifluoromethyl-pyridin-2-ylamine (CAS 1246466-70-5)
- 1-(2,5-Diaminophenyl)ethan-1-one (CAS 42465-63-4)
- 860195-69-3 6-Bromo-4-chloro-2-phenylquinoline DTXSID10588925 (CAS 860195-69-3)
- (3AR,7aS)-5-(4-fluorophenyl)-2,2-dimethyl-3a,7a-dihydrobenzo[d][1,3]dioxole (CAS 2199389-30-3)
- 8-Chloro-2-(3-isopropoxyphenyl)quinoline-4-carboxylic acid (CAS 862713-33-5)
- tert-Butyl 4-(2-ethoxy-2-oxoethyl)-4-fluoropiperidine-1-carboxylate (CAS 1235842-48-4)
- 2-chloro-3-fluoro-6-(trifluoromethyl)pyridine (CAS 1159512-39-6)
- Semaglutide-d5 (CAS CATO-C4X-2226153)
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