1-(2-Bromopyridin-4-yl)piperazine CAS 854159-48-1
| CAS No. | 854159-48-1 |
| Molecular Formula | C9H12BrN3 |
| Molecular Weight | 242.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(2-Bromopyridin-4-yl)piperazine.
1-(2-Bromopyridin-4-yl)piperazine (CAS 854159-48-1) is a high-purity analytical reference standard with the molecular formula C9H12BrN3 and a molecular weight of 242.12 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, bromine substitution, 1-(2-Bromopyridin-4-yl)piperazine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 242.12 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(2-Bromopyridin-4-yl)piperazine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H12BrN3 |
| Molecular Weight | 242.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 3 |
Related Bromopyridin Standards
- 1-(5-Bromopyridin-2-yl)piperazine (CAS 73406-97-0)
- 1-(6-Bromopyridin-2-yl)piperazine (CAS 219635-91-3)
- 1-(6-Bromopyridin-3-yl)piperazine (CAS 412347-39-8)
- 2-(5-Bromopyridin-2-yl)cyclopentan-1-ol (CAS 1420793-49-2)
- 1-(5-Bromopyridin-2-yl)butane-1,3-dione (CAS 1020042-37-8)
- 1-(6-Bromopyridin-2-yl)cyclopropane-1-carboxylic acid (CAS 1060811-40-6)
- 1-(2-Bromopyridin-4-yl)cyclopropane-1-carboxylic acid (CAS 1060811-43-9)
- 1-(5-Bromopyridin-3-yl)cyclopropane-1-carboxylic acid (CAS 1256038-40-0)
Recommended Standards
- [3-(methoxymethoxy)-1-naphthyl]boronic acid (CAS 2766628-35-5)
- 1-(5-Bromo-3-pyridyl)piperazine (CAS 412347-30-9)
- (E)-N'-(5-Bromo-3-methylpyridin-2-yl)-N,N-dimethylmethanimidamide (CAS 883052-76-4)
- (5S,8R)-3-bromo-5,6,7,8-tetrahydroquinoline-5,8-diamine (CAS 2053652-18-7)
- 2-(5-((3,4-Dichlorobenzyl)thio)-4-ethyl-4H-1,2,4-triazol-3-yl)thieno[2,3-b]quinoline (CAS 478260-38-7)
- 2-[(4-amino-2-chlorophenyl)formamido]-N,N-dimethylacetamide (CAS 1096794-02-3)
- (4-(1-Morpholinoethyl)phenyl)boronic acid hydrochloride (CAS 1704069-64-6)
- 1-Benzyl-4-(methylsulfonyl)piperazine (CAS 118546-61-5)
- 3-(Methylthio)-N-(4-phenylthiazol-2-yl)benzamide (CAS 896356-12-0)
- Rivaroxaban Impurity 171 (CAS CATO-C4X-1090171)
- N-Benzyl-1-(difluoromethyl)-3-methyl-1H-pyrazol-4-amine hydrochloride (CAS 1856085-45-4)
- (S)-4'-(2-Methylbutyl)-[1,1'-biphenyl]-4-carboxylic acid (CAS 62614-48-6)
- 2-((5-(4-Chlorophenyl)-4-(p-tolyl)-4H-1,2,4-triazol-3-yl)thio)-N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)acetamide (CAS 477331-34-3)
- Exenatide Acetate (CAS 141732-76-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com