(2E)-3-[4-(cyanomethoxy)phenyl]acrylic acid CAS 854357-48-5

Purity 97%+In StockPharmaceutical Standards
CAS No.854357-48-5
Molecular FormulaC11H9NO3
Molecular Weight203.19 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(2E)-3-[4-(cyanomethoxy)phenyl]acrylic acid CAS 854357-48-5 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (2E)-3-[4-(cyanomethoxy)phenyl]acrylic acid.

CATO supplies (2E)-3-[4-(cyanomethoxy)phenyl]acrylic acid (CAS 854357-48-5), a certified reference material (molecular formula C11H9NO3, MW 203.19 g/mol) for analytical method development and quality control.

Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, (2E)-3-[4-(cyanomethoxy)phenyl]acrylic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 203.19 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), (2E)-3-[4-(cyanomethoxy)phenyl]acrylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC11H9NO3
Molecular Weight203.19 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Nitrogen Atoms1

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