Caffeine Impurity 11 CAS 85438-96-6
| CAS No. | 85438-96-6 |
| Molecular Formula | C8H10N4O4 |
| Molecular Weight | 226.19 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Caffeine Impurity 11 is closely related to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Caffeine Impurity 11 (CAS 85438-96-6, C8H10N4O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, Caffeine Impurity 11 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 226.19 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Caffeine Impurity 11 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H10N4O4 |
| Molecular Weight | 226.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1981 |
| Nitrogen Atoms | 4 |
Related Caffeine Standards
Recommended Standards
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- Ketotifen Impurity 14 (CAS CATO-C4X-204614)
- Salbutamol Impurity 218 (CAS CATO-C4X-1176218)
- Eltrombopag Impurity 49 (CAS 67666-03-9)
- 4-Methoxybenzyl imidothiocarbamate hydrochloride (CAS 25985-08-4)
- 3-Iodo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine (CAS 1955523-82-6)
- N-(2-Oxo-1,2-dihydropyrimidin-4-yl)isobutyramide (CAS 97626-98-7)
- 2-(2-(1H-Pyrrol-1-yl)thiazol-4-yl)-N-(4-sulfamoylphenethyl)acetamide (CAS 1172695-36-1)
- tert-Butyl N-(1-amino-3-hydroxypropan-2-yl)carbamate (CAS 1429913-75-6)
- 2-Chloro-N-(1-(2,4-dichlorobenzyl)-1H-pyrazol-3-yl)acetamide (CAS 1004643-27-9)
- Tirzepatide Impurity 18 (CAS CATO-C4X-324018)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com