(E)-3-(1H-Indol-3-yl)acrylonitrile CAS 85452-78-4

Purity 97%+In StockPharmaceutical Standards
CAS No.85452-78-4
Molecular FormulaC11H8N2
Molecular Weight168.19 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(E)-3-(1H-Indol-3-yl)acrylonitrile CAS 85452-78-4 chemical structure

Description

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

(E)-3-(1H-Indol-3-yl)acrylonitrile (CAS 85452-78-4) is a high-purity analytical reference standard with the molecular formula C11H8N2 and a molecular weight of 168.19 g/mol.

The molecular framework of (E)-3-(1H-Indol-3-yl)acrylonitrile (C11H8N2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

As a certified reference material (CRM), (E)-3-(1H-Indol-3-yl)acrylonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC11H8N2
Molecular Weight168.19 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1981
Nitrogen Atoms2

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