Bis(4-fluorophenyl)methyl(chloromethyl)silane CAS 85491-26-5
| CAS No. | 85491-26-5 |
| Molecular Formula | C14H13ClF2Si |
| Molecular Weight | 282.79 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 282.79 g/mol gives Bis(4-fluorophenyl)methyl(chloromethyl)silane distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Bis(4-fluorophenyl)methyl(chloromethyl)silane (CAS 85491-26-5), a certified reference material (molecular formula C14H13ClF2Si, MW 282.79 g/mol) for analytical method development and quality control.
The molecular framework of Bis(4-fluorophenyl)methyl(chloromethyl)silane (C14H13ClF2Si) is characterized by fluorine/chlorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H13ClF2Si |
| Molecular Weight | 282.79 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1981 |
| Halogen Content | F/Cl-containing |
Related Bis Standards
- 4-((4-Fluorophenyl)thio)butane-1-sulfonyl chloride (CAS 1375067-81-4)
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- 2-(4-FLuorophenyl)-2-(1,1,2,2,2-pentafluoroethyl)pyrrolidine (CAS 887360-97-6)
- 3-((4-Fluorophenyl)thio)-N-(thiazol-2-yl)propanamide (CAS 896356-26-6)
- N-(2-fluorophenyl)-3-(trifluoromethyl)benzamide (CAS 199461-55-7)
- N-(3-Fluorophenyl)-2-(trifluoromethyl)benzamide (CAS 838888-36-1)
- N-(4-fluorophenyl)-3-(trifluoromethyl)benzamide (CAS 33489-71-3)
- 154554-41-3 2-(2-fluorophenyl)-6,7-methylenedioxy-2-4-quinolone hydrate, NSC 656158 (CAS 154554-41-3)
Recommended Standards
- 7-chloro-2-mercapto-3-(3-methylbutyl)quinazolin-4(3H)-one (CAS 422526-52-1)
- Paliperidone Impurity 162 (CAS CATO-C4X-1724162)
- 5-(((3-Chloro-4-methylphenyl)amino)methyl)-4-ethyl-4H-1,2,4-triazole-3-thiol (CAS 333313-76-1)
- 4′-Fluorobiphenyl-4-sulfonyl chloride (CAS 116748-66-4)
- 1-(4-methylmorpholin-2-yl)ethan-1-amine (CAS 1421603-49-7)
- 4-((6-(Methylthio)-9H-purin-9-yl)amino)butane-1,2,3-triol (CAS 57464-47-8)
- (2R)-2-{[(benzyloxy)carbonyl]amino}-2-[3-(trifluoromethyl)bicyclo[1.1.1]pentan-1-yl]acetic acid (CAS 1993319-93-9)
- 6,8-Dimethyl-4-oxo-1,4-dihydrocinnoline-3-carboxylic acid (CAS 36991-59-0)
- 2,4-Dimethyl-1,1'-biphenyl (CAS 4433-10-7)
- NDT 9513727 (CAS 439571-48-9)
- 3-(5-bromothiophen-2-yl)-4-(4-fluorophenyl)-1,2-oxazol-5-amine (CAS 1097153-77-9)
- 3-[ethyl(phenyl)sulfamoyl]benzoic acid (CAS 325721-87-7)
- Trazodone Impurity 30 (CAS 79975-63-6)
- Semaglutide Impurity 155 (x TFA Salt) (CAS CATO-C4X-2226155)
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