Aspirin impurity 30 CAS 85531-18-6
| CAS No. | 85531-18-6 |
| Molecular Formula | C28H18O9 |
| Molecular Weight | 498.44 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Aspirin impurity 30 (C28H18O9) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Aspirin impurity 30 (CAS 85531-18-6, C28H18O9) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C28H18O9 |
| Molecular Weight | 498.44 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 20.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1981 |
Related Aspirin Standards
Recommended Standards
- N-({1'-benzyl-4',5'-dimethyl-1'H-[1,2'-bipyrrole]-3'-yl}methyl)-4-bromobenzene-1-sulfonamide (CAS 478077-22-4)
- 1,3-Dimethyl 5,5-dicyano-2-hydroxy-6-(4-methylphenyl)-4-[3-(trifluoromethyl)phenyl]cyclohex-1-ene-1,3-dicarboxylate (CAS 1212217-00-9)
- 1,1'-BIs[(2S,4S)-2,4-bis(1-methylethyl)-1-phosphetanyl]ferrocene (CAS 224057-12-9)
- (2Z)-3-[3-(4-Cyclohexylphenyl)-1-phenyl-1H-pyrazol-4-yl]-2-(2,4-dichlorophenyl)prop-2-enenitrile (CAS 956606-89-6)
- Chlorpromazine EP Impurity B DiHCl (CAS 19077-20-4)
- Levosimendan Impurity 60 (CAS CATO-C4X-130860)
- Troxipide Impurity 15 (CAS CATO-C4X-214815)
- 3-(3-AMino-5-chloro-2-oxo-2h-pyrazin-1-yl)-benzoic acid methyl ester (CAS 1820712-46-6)
- Nintedanib Impurity 21 (CAS CATO-C4X-181421)
- 3-(3-Chloro-4-fluorophenoxy)propanenitrile (CAS 1343192-11-9)
- Pranoprofen Impurity 24 (CAS CATO-C4X-181124)
- 368-43-4 Phenylsulfonylfluoride Benzenesulfonyl fluoride Benzenesulphonyl fluoride 4-11-00-00049 (Beilstein Handbook Reference) BRN 2206835 EINECS 206-707-2 NSC 8543 Phenylsulfonyl fluoride (CAS 368-43-4)
- 4-(2,2,3,3-Tetrafluoropropoxy)aniline hydrochloride (CAS 109230-81-1)
- Peptide Impurity 28 (CAS 1350456-64-2)
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