Methocarbamol Impurity 10 CAS 85536-84-1
| CAS No. | 85536-84-1 |
| Molecular Formula | C13H18O6 |
| Molecular Weight | 270.28 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Methocarbamol Impurity 10 (CAS 85536-84-1, C13H18O6) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Methocarbamol Impurity 10 (C13H18O6) contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H18O6 |
| Molecular Weight | 270.28 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1981 |
Related Methocarbamol Standards
- Methocarbamol Impurity 11 (CAS CATO-C4X-244411)
- Methocarbamol Impurity 5 (CAS CATO-C4X-24445)
- Methocarbamol Impurity 2 (CAS CATO-C4X-24442)
- Methocarbamol-D5 (CAS 1189699-70-4)
- Methocarbamol D3 (CAS 1346600-86-9)
- Methocarbamol Impurity 4 (CAS CATO-C4X-24444)
- (S)-Methocarbamol (CAS 108914-10-9)
- (R)-Methocarbamol (CAS 145841-69-6)
Recommended Standards
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