4-(1,1,2,2-Tetrafluoroethoxy)phenol CAS 85578-29-6
| CAS No. | 85578-29-6 |
| Molecular Formula | C8H6F4O2 |
| Molecular Weight | 210.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(1,1,2,2-Tetrafluoroethoxy)phenol.
4-(1,1,2,2-Tetrafluoroethoxy)phenol (CAS 85578-29-6), molecular formula C8H6F4O2 and molecular weight 210.13 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-(1,1,2,2-Tetrafluoroethoxy)phenol (C8H6F4O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-(1,1,2,2-Tetrafluoroethoxy)phenol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H6F4O2 |
| Molecular Weight | 210.13 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1981 |
| Halogen Content | F-containing |
Related Tetrafluoroethoxy Standards
- 2-(1,1,2,2-tetrafluoroethoxy)phenol (CAS 88553-88-2)
- 3-(1,1,2,2-Tetrafluoroethoxy)phenol (CAS 53997-99-2)
- 2-(1,1,2,2-Tetrafluoroethoxy)aniline (CAS 35295-34-2)
- 3-(1,1,2,2-Tetrafluoroethoxy)aniline (CAS 831-75-4)
- 4-(1,1,2,2-Tetrafluoroethoxy)aniline (CAS 713-62-2)
- ((1,1,2,2-Tetrafluoroethoxy)methyl)benzene (CAS 115611-57-9)
- 3-(1,1,2,2-Tetrafluoroethoxy)toluene (CAS 1737-10-6)
- 4-(1,1,2,2-Tetrafluoroethoxy)toluene (CAS 1737-11-7)
Recommended Standards
- 4-Methoxy-2,3,5,6-tetrafluorobenzyl alcohol (CAS 35175-79-2)
- 2-Fluoro-3-(trifluoromethoxy)benzyl alcohol (CAS 86256-43-1)
- D-β-Homoselenomethionine (CAS 2044709-68-2)
- 2,5-Dimethylbenzo[d][1,3]selenazole (CAS 2818-89-5)
- 4-Chloro-5-methyl-N1-phenylbenzene-1,2-diamine (CAS 861519-25-7)
- 2-(2,4-Dichlorophenoxy)-6-(3,4-dichlorophenyl)pyridine-3-carbonitrile (CAS 252059-72-6)
- 5-Fluoro-1,3-benzoxazole-7-carboxylic acid (CAS 1258702-18-9)
- 5-(4-Chlorophenyl)-5-oxopentanoic acid (CAS 36978-49-1)
- 5-Methyl-1-phenyl-1,3-hexanedione (CAS 13893-97-5)
- Fmoc-4-phosphono-Phe(Bzl)-OH (CAS 943148-45-6)
- Desloratadine Impurity 36 (CAS 1193725-75-5)
- 2-((4-Bromophenyl)thio)cyclopentan-1-one (CAS 1154284-48-6)
- 1-Amino-3-methylbutane-2,3-diol (CAS 1236226-80-4)
- Semaglutide impurity 237 (CAS CATO-C4X-2226237)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com