4-Hydroxy-2-oxo-1,2-dihydropyridine-3-carboxylic acid CAS 856214-16-9
| CAS No. | 856214-16-9 |
| Molecular Formula | C6H5NO4 |
| Molecular Weight | 155.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Hydroxy-2-oxo-1,2-dihydropyridine-3-carboxylic acid (CAS 856214-16-9), molecular formula C6H5NO4 and molecular weight 155.11 g/mol, is a CATO reference standard with documented purity and traceability.
4-Hydroxy-2-oxo-1,2-dihydropyridine-3-carboxylic acid (C6H5NO4) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Hydroxy-2-oxo-1,2-dihydropyridine-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H5NO4 |
| Molecular Weight | 155.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 1 |
Related Hydroxy Standards
- 6-Hydroxy-2-oxo-1,2-dihydropyridine-3-carboxylic acid (CAS 10357-91-2)
- 3-Hydroxy-2-oxo-1,2-dihydropyridine-4-carboxylic acid (CAS 1174332-60-5)
- 1-Hydroxy-2-oxo-1,2-dihydropyridine-4-carboxylic acid (CAS 119736-22-0)
- 5-Hydroxy-2-oxo-1,2-dihydropyridine-4-carboxylic acid (CAS 132829-86-8)
- (E)-3-(3-hydroxy-1H-1,2,4-triazol-5-yl)acrylic acid (CAS 1394306-92-3)
- N-Hydroxy-3-oxo-3,4-dihydropyrazine-2-carboxamide (CAS 185949-08-0)
- 5-Hydroxy-4-oxo-1,4-dihydropyridine-3-carboxylic acid (CAS 1909302-71-1)
- 1-Hydroxy-2-oxo-1,2-dihydropyridine-3-carboxylic acid (CAS 202118-70-5)
Recommended Standards
- 4-Formyl-3-methylisoxazole-5-carboxylic acid (CAS 256473-81-1)
- 4-Hydroxy-6-oxo-1,6-dihydropyrimidine-5-carbaldehyde oxime (CAS 29955-37-1)
- 4-Amino-6-hydroxypyrimidine-2-carboxylic acid (CAS 5177-21-9)
- 4-Nitro-1,3-benzenediol (CAS 3163-07-3)
- Ethyl 2-(3-bromo-5-chloropyridin-2-yl)acetate (CAS 1807220-75-2)
- (R)-5-(piperidin-1-ylmethyl)-3-(pyridin-3-yl)-5,6-dihydro-2H-1,2,4-oxadiazine (CAS 203805-20-3)
- N2-phenyl-1,3,5-triazine-2,4-diamine hydrochloride (CAS 6011-10-5)
- (1R,9aR)-octahydro-2H-quinolizine-1-carboxylic acid hydrochloride (CAS 16100-92-8)
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