(Z)-3-((1H-Indol-3-yl)methylene)-6-chloroindolin-2-one CAS 856435-34-2
| CAS No. | 856435-34-2 |
| Molecular Formula | C17H11ClN2O |
| Molecular Weight | 294.74 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
(Z)-3-((1H-Indol-3-yl)methylene)-6-chloroindolin-2-one (CAS 856435-34-2), molecular formula C17H11ClN2O and molecular weight 294.74 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (Z)-3-((1H-Indol-3-yl)methylene)-6-chloroindolin-2-one (C17H11ClN2O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H11ClN2O |
| Molecular Weight | 294.74 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- (3E)-3-[(4-Chlorophenyl)imino]-1-(prop-2-yn-1-yl)-2,3-dihydro-1H-indol-2-one (CAS 338400-57-0)
- 1-(4-Chlorobenzoyl)-1,2-dihydroquinoline-2-carbonitrile (CAS 94540-23-5)
- 2-(4-Chlorophenyl)-1H,2H,3H-pyrrolo[3,4-b]quinolin-1-one (CAS 180161-75-5)
- 1-Benzyl-6-chloro-2-oxo-1,2-dihydroquinoline-3-carbonitrile (CAS 89479-58-3)
- (3S,4R)-4-isobutylpyrrolidin-3-ol (CAS 1242166-63-7)
- 2-Allylpyrrolidine hydrochloride (CAS 245725-70-6)
- 5-(5-Methoxy-2-bromophenyl)-1,3-oxazole (CAS 2017137-72-1)
- 3-(3-(Trifluoromethyl)phenyl)pyrrolidin-3-ol hydrochloride (CAS 1744-48-5)
- 3-(3,4-Dichlorophenoxy)piperidine (CAS 946714-37-0)
- 2-(4-(Isopentyloxy)phenyl)ethan-1-ol (CAS 106379-94-6)
- 2-Chloro-4-phenylthiazole-5-sulfonyl chloride (CAS 2138159-10-9)
- 4-(4-(Ethoxycarbonyl)benzoyl)benzoic acid (CAS 113709-91-4)
- 3-((Thiazol-5-ylmethyl)amino)benzonitrile (CAS 1341132-26-0)
- Fas C- Terminal Tripeptide (CAS 189109-90-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com