(R)-1-(4-Chloro-2-fluorophenyl)ethan-1-amine hydrochloride CAS 856562-91-9
| CAS No. | 856562-91-9 |
| Molecular Formula | C8H9ClFN |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of (R)-1-(4-Chloro-2-fluorophenyl)ethan-1-amine hydrochloride (C8H9ClFNHCl) is characterized by a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
(R)-1-(4-Chloro-2-fluorophenyl)ethan-1-amine hydrochloride (CAS 856562-91-9) is a high-purity analytical reference standard with the molecular formula C8H9ClFNHCl and a molecular weight of 210.07 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (R)-1-(4-Chloro-2-fluorophenyl)ethan-1-amine hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H9ClFN HCl |
| Molecular Weight | 210.07 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
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- 1-(((4-Methyl-4H-1,2,4-triazol-3-yl)thio)methyl)cyclopentan-1-ol (CAS 1498519-48-4)
- Fragment-[7-31]-Liraglutide (CAS CATO-C4X-199239)
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