5-Hydrazinyl-1,2,4-thiadiazole CAS 856653-33-3
| CAS No. | 856653-33-3 |
| Molecular Formula | C2H4N4S |
| Molecular Weight | 116.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-Hydrazinyl-1,2,4-thiadiazole is closely related to a nitrile group, sulfur-containing functionality in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
5-Hydrazinyl-1,2,4-thiadiazole (CAS 856653-33-3) is a high-purity analytical reference standard with the molecular formula C2H4N4S and a molecular weight of 116.14 g/mol.
The molecular framework of 5-Hydrazinyl-1,2,4-thiadiazole (C2H4N4S) is characterized by a nitrile group, sulfur-containing functionality. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Hydrazinyl-1,2,4-thiadiazole under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C2H4N4S |
| Molecular Weight | 116.14 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Hydrazinyl Standards
- 2-Hydrazinyl-1,3,4-thiadiazole (CAS 30094-47-4)
- 2-Hydrazinyl-4,5-dihydrothiazole (CAS 45439-41-6)
- 2-Hydrazinyl-1,4,5,6-tetrahydropyrimidine (CAS 55110-65-1)
- 4-Hydrazinyl-1-methyl-1H-pyrazole (CAS 1268521-80-7)
- 3-Hydrazinyl-5-methylpyridine (CAS 1035173-64-8)
- 4-Hydrazinyl-3-methylpyridine (CAS 114913-51-8)
- 3-Hydrazinyl-2-methylpyridine (CAS 160590-37-4)
- 2-Hydrazinyl-4-methylpyridine (CAS 4931-00-4)
Recommended Standards
- 5-Amino-1,3-thiazol-2-ol (CAS 98026-69-8)
- 5-Methyl-1,3,4-oxadiazole-2(3H)-thione (CAS 31130-17-3)
- 4-Iminothiazolidin-2-one (CAS 19967-65-8)
- Cyclohexylphosphine, min. 97% (10 wt% in hexanes) (CAS 822-68-4)
- Ethyl 8-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxylate (CAS 34667-64-6)
- 1-(2,2-diethoxyethyl)-1H-1,2,4-triazole-3-carbonitrile (CAS 1338990-15-0)
- 2-Bromo-3-(2,5-dimethoxyphenyl)-1-propene (CAS 951891-17-1)
- (E)-{1-[2-(4-chlorophenyl)-4-methyl-1,3-thiazol-5-yl]ethylidene}amino 4-fluorobenzoate (CAS 477872-46-1)
- 4-Bromo-3-chloro-2,5-difluorobenzoic acid (CAS 2487480-03-3)
- 2-(4-(4-Ethoxy-3-methylphenyl)-2-propionamidothiazol-5-yl)acetic acid (CAS 1416345-64-6)
- 2-((3-Chlorophenyl)sulfonyl)-N-(3-(trifluoromethyl)phenyl)acetamide (CAS 339107-31-2)
- 5,6,7,8,9,10-Hexahydro-7,10-epiminocycloocta[c]pyridine (CAS 105282-59-5)
- 4-Chloro-7-(phenylsulfonyl)-7H-pyrrolo-[2,3-d]pyrimidine-6-carboxylic acid (CAS 1346447-16-2)
- Semaglutide impurity 215 (CAS CATO-C4X-2226215)
Why CATO?
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