1,2-difluoro-4,5- dinitrobenzene CAS 85686-97-1
| CAS No. | 85686-97-1 |
| Molecular Formula | C6H2F2N2O4 |
| Molecular Weight | 204.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
1,2-difluoro-4,5- dinitrobenzene (CAS 85686-97-1), molecular formula C6H2F2N2O4 and molecular weight 204.09 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1,2-difluoro-4,5- dinitrobenzene (C6H2F2N2O4) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 1,2-difluoro-4,5- dinitrobenzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H2F2N2O4 |
| Molecular Weight | 204.09 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1981 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
- 4-Amino-2-bromobenzenethiol (CAS 15178-54-8)
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- 5-Bromo-4-methylpyridine-2-thiol (CAS 1403579-62-3)
- N-(4-(1H-Benzo[d]imidazol-2-yl)phenyl)-2,4-dimethoxybenzamide (CAS 476633-98-4)
- 5-(Thiophen-3-yl)oxazolidine-2,4-dione (CAS 82069-43-0)
- 5-amino-1,3,4,5-tetrahydro-2h-benzo[b]azepin-2-one (CAS 933691-92-0)
- Halcinonide Impurity 13 (CAS CATO-C4X-279513)
- 1-((3,5-Dimethyl-1H-pyrazol-4-yl)sulfonyl)pyrrolidine-3-carboxylic acid (CAS 1404853-95-7)
- 3-(3-Oxo-4-phenyl-3,4-dihydroquinoxalin-2-yl)propanoic acid (CAS 934063-51-1)
- Methyl glycylglycylglycinate (CAS 31681-05-7)
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- trimethyl-[2-(1-methylpyrazol-4-yl)ethynyl]silane (CAS 1201657-09-1)
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