4-(Methylsulfonyl)pyridin-3-amine CAS 857220-38-3
| CAS No. | 857220-38-3 |
| Molecular Formula | C6H8N2O2S |
| Molecular Weight | 172.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-(Methylsulfonyl)pyridin-3-amine (C6H8N2O2S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
4-(Methylsulfonyl)pyridin-3-amine (CAS 857220-38-3) is a high-purity analytical reference standard with the molecular formula C6H8N2O2S and a molecular weight of 172.20 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-(Methylsulfonyl)pyridin-3-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H8N2O2S |
| Molecular Weight | 172.20 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Methylsulfonyl Standards
- 5-(methylsulfonyl)pyridin-3-amine (CAS 1067530-19-1)
- 4-(Methylsulfonyl)pyridin-2-amine (CAS 1379357-46-6)
- 3-(Methylsulfonyl)phenol (CAS 14763-61-2)
- 3-(Methylsulfonyl)pyridin-4-amine (CAS 1780687-87-7)
- 2-(Methylsulfonyl)phenol (CAS 27489-33-4)
- 2-(Methylsulfonyl)pyridin-4-amine (CAS 944401-88-1)
- 3-(Methylsulfonyl)pyridin-2-amine (CAS 878805-97-1)
- 4-Methyl-2-(methylsulfonyl)pyrimidine (CAS 77166-01-9)
Recommended Standards
- 4-(2-Hydroxyethyl)thiophene-2-carboxylic acid (CAS 2090045-09-1)
- 4,6-Dimethoxypyrimidine-2-thiol (CAS 57235-35-5)
- 3-Methylpyridine-2-sulfonic acid amide (CAS 65938-79-6)
- 4-Ethoxythiophene-2-carboxylic acid (CAS 917980-53-1)
- 4-((4-(2-Fluorophenyl)piperazin-1-yl)sulfonyl)morpholine (CAS 712345-40-9)
- 1,1-Dimethyl-3-(5-oxo-2-(trifluoromethyl)-5H-chromeno[2,3-b]pyridin-3-yl)urea (CAS 303995-23-5)
- Palladium(II) Acetate Trimer (CAS 53189-26-7)
- tert-Butyl 8-formyl-6-azaspiro[3.4]octane-6-carboxylate (CAS 2137718-90-0)
- N-(3-Methyl-4-(N-(thiophen-3-ylmethyl)sulfamoyl)phenyl)acetamide (CAS 1060230-30-9)
- 2-(Naphthalen-2-yloxy)ethanamine Hydrochloride (CAS 859338-95-7)
- 1-(5-Phenyl-1H-1,2,4-triazol-3-yl)urea (CAS 6642-32-6)
- Methyl 4-((1-methyl-4-nitro-1H-pyrazol-3-yl)oxy)benzoate (CAS 1443278-98-5)
- 2-((1-Cyanocyclohexyl)amino)-2-oxoethyl 2-(2-chloro-6-fluorophenyl)acetate (CAS 877831-41-9)
- Tirzepatide Impurity 10 (CAS CATO-C4X-324010)
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