1-(2-Chloro-4-nitro-1H-imidazol-1-yl)-3-phenoxypropan-2-ol CAS 857495-83-1
| CAS No. | 857495-83-1 |
| Molecular Formula | C12H12ClN3O4 |
| Molecular Weight | 297.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 1-(2-Chloro-4-nitro-1H-imidazol-1-yl)-3-phenoxypropan-2-ol (CAS 857495-83-1), a certified reference material (molecular formula C12H12ClN3O4, MW 297.69 g/mol) for analytical method development and quality control.
1-(2-Chloro-4-nitro-1H-imidazol-1-yl)-3-phenoxypropan-2-ol (C12H12ClN3O4) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H12ClN3O4 |
| Molecular Weight | 297.69 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 1-(5-Chloro-2-methoxyphenyl)-5-(methoxymethyl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1326837-98-2)
- 1-(5-Chloro-2,4-dimethoxyphenyl)-5-methyl-1H-1,2,3-triazole-4-carboxylic acid (CAS 1351831-02-1)
- (4S)-7-Chloro-4-ethyl-4-hydroxy-7,8-dihydro-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione (CAS 748799-31-7)
- 2,2'-(((5-Chloro-1H-benzo[d]imidazol-2-yl)methyl)azanediyl)diacetic acid (CAS 72998-94-8)
- 8-Chloro-2-(4-hydroxyphenyl)-4-oxo-4H-chromene-7-carbonitrile (CAS 2413193-57-2)
- 5-(2-CHloro-5-(trifluoromethyl)phenyl)isoindoline (CAS 1206970-34-4)
- (2-Chloro-6-morpholin-4-yl-9H-purin-9-yl)acetic acid (CAS 1374408-06-6)
- 2-Chloro-9-methyl-6-morpholino-9H-purine-8-carboxylic acid (CAS 1439824-88-0)
Recommended Standards
- 5-(tert-Butyl)-3-(2-chloro-4-nitrophenyl)-1,3,4-oxadiazol-2(3H)-one (CAS 31399-83-4)
- N-(4-Chlorophenyl)-2,2-difluoro-2-phenoxyacetamide (CAS 338791-86-9)
- Nimodipine Impurity 2 (CAS 62760-01-4)
- Ethyl 6-chloro-2-(2,4-difluorophenyl)pyridine-3-carboxylate (CAS 745833-19-6)
- 5-(Aminomethyl)-5-methylimidazolidine-2,4-dione hydrochloride (CAS 1009640-21-4)
- 1,3-Bis(1-methyl-1h-pyrazol-5-yl)propane-1,3-dione (CAS 1006328-59-1)
- (3AS,5R,6aS)-1-(tert-butoxycarbonyl)octahydrocyclopenta[b]pyrrole-5-carboxylic acid (CAS 1251006-61-7)
- 9-Butyl-2,3,5,6,7,8-hexahydroacridin-4(1H)-one (CAS 99922-92-6)
- 1-(5-Chloro-7-methylbenzofuran-2-yl)-2-methylpropan-1-amine (CAS 1489492-55-8)
- 3-(5-(4-Methoxyphenyl)furan-2-yl)acrylic acid (CAS 62806-31-9)
- 3-Amino-3-(4-bromothiophen-2-yl)propanoic acid (CAS 194229-25-9)
- ((2S,3R)-3-methylmorpholin-2-yl)methanol (CAS 2366180-32-5)
- Levonorgestrel Impurity 43 (CAS 2762739-33-1)
- Fibrinopeptide A, human TFA (CAS 61533-47-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com