tert-Butyl 4-{[3-(pyridin-4-yl)-1,2,4-oxadiazol-5-yl]methyl}piperidine-1-carboxylate CAS 857652-40-5
| CAS No. | 857652-40-5 |
| Molecular Formula | C18H24N4O3 |
| Molecular Weight | 344.41 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
tert-Butyl 4-{[3-(pyridin-4-yl)-1,2,4-oxadiazol-5-yl]methyl}piperidine-1-carboxylate (CAS 857652-40-5) is a high-purity analytical reference standard with the molecular formula C18H24N4O3 and a molecular weight of 344.41 g/mol.
The molecular framework of tert-Butyl 4-{[3-(pyridin-4-yl)-1,2,4-oxadiazol-5-yl]methyl}piperidine-1-carboxylate (C18H24N4O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H24N4O3 |
| Molecular Weight | 344.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 4 |
Recommended Standards
- Tert-butyl 4-(3-(3-cyanophenyl)ureido)piperidine-1-carboxylate (CAS 198823-38-0)
- Saxagliptin Impurity 85 (CAS CATO-C4X-104985)
- N1,N2-dibenzylphthalamide (CAS 38228-99-8)
- Ilaprazole Impurity 149 (CAS CATO-C4X-1130149)
- 4-(2-Sulfanylidene-2,3-dihydro-1H-1,3-benzodiazol-1-yl)butanoic acid (CAS 1459280-12-6)
- Ethyl 6-ethyl-4-thioxo-1,4-dihydroquinoline-3-carboxylate (CAS 1279208-94-4)
- 3-Butoxypropanoic acid (CAS 7420-06-6)
- 2-(2-Chlorophenyl)-1-phenylmethanesulfonylpropan-2-ol (CAS 339276-83-4)
- 2-(2-Bromoethyl)-1,2-thiazolidine-1,1-dione (CAS 1157050-15-1)
- 2-Bromo-3-chloro-4-(difluoromethyl)-5-iodopyridine (CAS 1806932-74-0)
- N1,N2-bis(4-methoxyphenyl)oxalamide (CAS 3299-63-6)
- Ethyl 2-(Boc-amino)-3-[4-(benzyloxy)phenyl]-3-phenylacrylate (CAS 2006281-57-6)
- 5-Cyclopropyl-N,N-dimethylpyridin-2-amine (CAS 1245645-43-5)
- Semaglutide impurity 267 (CAS CATO-C4X-2226267)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com