Rolapitant Hydrochloride CAS 858102-79-1
| CAS No. | 858102-79-1 |
| Molecular Formula | C25H26F6N2O2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C25H26F6N2O2HCl, Rolapitant Hydrochloride contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 536.94 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies Rolapitant Hydrochloride (CAS 858102-79-1), a certified reference material (molecular formula C25H26F6N2O2HCl, MW 536.94 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Rolapitant Hydrochloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C25H26F6N2O2 HCl |
| Molecular Weight | 536.94 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Rolapitant Standards
Recommended Standards
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- 2-Phenoxy-1-(7-(thiophen-2-yl)-1,4-thiazepan-4-yl)ethan-1-one (CAS 1705245-52-8)
- 1-(3-Chloro-2-fluorophenyl)-5-oxopyrrolidine-3-carboxylic acid (CAS 1152531-47-9)
- 2-(Chlorocarbonyl)benzoic acid (CAS 30247-86-0)
- 2-(2-Aminobenzo[d]oxazol-6-yl)acetic acid (CAS 1453089-60-5)
- 4-(4-Chlorophenyl)-2-fluorophenol (CAS 1261944-84-6)
- Ethoxydimethylsilanol (CAS 65007-35-4)
- N,N-Dibutylbenzenesulfonamide (CAS 5339-59-3)
- 1,5-Dichloroacenaphthene (CAS 669047-83-0)
- D-allo-Thr7-Semaglutide (CAS CATO-C4X-2226242)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com