3-(Chloromethyl)pyridin-2-amine hydrochloride CAS 858431-27-3
| CAS No. | 858431-27-3 |
| Molecular Formula | C6H7ClN2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
3-(Chloromethyl)pyridin-2-amine hydrochloride (CAS 858431-27-3), molecular formula C6H7ClN2HCl and molecular weight 179.04 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-(Chloromethyl)pyridin-2-amine hydrochloride (C6H7ClN2HCl) is characterized by a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 3-(Chloromethyl)pyridin-2-amine hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H7ClN2 HCl |
| Molecular Weight | 179.04 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloromethyl Standards
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Recommended Standards
- N-(But-3-yn-1-yl)cyclopropanecarboxamide (CAS 1340100-56-2)
- 2-(2,6-dioxo-3-piperidyl)-4-[3-(methylamino)propylamino]isoindoline-1,3-dione (CAS 2736496-77-6)
- 28240-71-3 CTK4G1069 Phosphonous dichloride,P,P'-1,4-butanediylbis- (CAS 28240-71-3)
- [(2-aminobutyl)sulfanyl]benzene (CAS 3898-25-7)
- 2-(Difluoromethyl)-6-hydroxy-3-methoxypyridine-4-acetonitrile (CAS 1806941-14-9)
- 5-Chloro-N-[2-(4-methoxyphenoxy)propyl]-2-methylaniline (CAS 1040684-97-6)
- 4-Phenyl-1,3-benzothiazol-2-amine (CAS 21418-32-6)
- 4-Chloro-5,6,7,8-tetrahydrophthalazin-1-amine (CAS 90006-64-7)
- (E)-2-Styrylpyrimidine (CAS 35782-30-0)
- Acetyl tetrapeptide-9(Dermican LS 9837) (CAS 928006-50-2)
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