2-(2,2,2-Trifluoroethyl)benzoic acid CAS 858847-76-4
| CAS No. | 858847-76-4 |
| Molecular Formula | C9H7F3O2 |
| Molecular Weight | 204.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(2,2,2-Trifluoroethyl)benzoic acid (CAS 858847-76-4), molecular formula C9H7F3O2 and molecular weight 204.15 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-(2,2,2-Trifluoroethyl)benzoic acid (C9H7F3O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-(2,2,2-Trifluoroethyl)benzoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H7F3O2 |
| Molecular Weight | 204.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
Related Trifluoroethyl Standards
- 3-(2,2,2-Trifluoroethyl)benzoic acid (CAS 114980-36-8)
- 4-(2,2,2-Trifluoroethyl)benzoic acid (CAS 1176282-86-2)
- 2,2,2-Trifluoroethyl benzoate (CAS 1579-72-2)
- (3-(2,2,2-Trifluoroethyl)phenyl)boronic acid (CAS 1620056-82-7)
- (6-(2,2,2-Trifluoroethyl)pyridin-3-yl)boronic acid (CAS 1356109-90-4)
- 1-(3-(2,2,2-Trifluoroethyl)phenyl)ethan-1-amine (CAS 1465485-52-2)
- 2-Ethyl-4-(2,2,2-trifluoroethyl)aniline (CAS 476335-33-8)
- 6-(2,2,2-Trifluoroethyl)picolinic acid (CAS 1256812-05-1)
Recommended Standards
- 2-(1-(Trifluoromethyl)cyclopropyl)pyrimidin-5-ol (CAS 2167153-31-1)
- 2-(2,4,6-Trifluorophenyl)-1,3-dioxolane (CAS 773102-27-5)
- 1,3,5-Triethynyl-2,4,6-trifluorobenzene (CAS 674289-06-6)
- 2-(3-(Trifluoromethoxy)phenyl)acetaldehyde (CAS 944898-37-7)
- 3-Aminopropylphosphate (CAS 13138-33-5)
- 3-(3,5-Difluoro-4-methoxyphenyl)propanoic acid (CAS 105219-44-1)
- 1-Benzyl-3-phenyl-1-(3,3,3-trifluoro-2-hydroxypropyl)urea (CAS 478258-80-9)
- 3-Amino-4-fluorobenzyl bromide (CAS 1373232-88-2)
- 4-Cyclopropoxy-5-methoxypyridine-3-sulfonamide (CAS 1243361-33-2)
- 5-Amino-6-chloroquinoline (CAS 341010-40-0)
- tert-Butyl 4-(tert-butyl)thiazole-2-carboxylate (CAS 79247-76-0)
- 2,5-Difluoro-3-(trifluoromethyl)benzoic acid (CAS 1186195-28-7)
- (S)-5-(1-Amino-3-hydroxypropan-2-yl)-2-methoxyphenol (CAS 1212797-76-6)
- Neuroendocrine Regulatory Peptide-1 (rat) (CAS 954420-51-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com