Ethyl 6-amino-5-chloro-2-(4-chlorophenyl)-pyrimidine-4-carboxylate CAS 858955-37-0

Purity 97%+In StockPharmaceutical Standards
CAS No.858955-37-0
Molecular FormulaC13H11Cl2N3O2
Molecular Weight312.15 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Ethyl 6-amino-5-chloro-2-(4-chlorophenyl)-pyrimidine-4-carboxylate CAS 858955-37-0 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 312.15 g/mol gives Ethyl 6-amino-5-chloro-2-(4-chlorophenyl)-pyrimidine-4-carboxylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Ethyl 6-amino-5-chloro-2-(4-chlorophenyl)-pyrimidine-4-carboxylate (CAS 858955-37-0), a certified reference material (molecular formula C13H11Cl2N3O2, MW 312.15 g/mol) for analytical method development and quality control.

Ethyl 6-amino-5-chloro-2-(4-chlorophenyl)-pyrimidine-4-carboxylate (C13H11Cl2N3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures Ethyl 6-amino-5-chloro-2-(4-chlorophenyl)-pyrimidine-4-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC13H11Cl2N3O2
Molecular Weight312.15 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Halogen ContentCl-containing
Nitrogen Atoms3

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