2-Trifluoromethylbenzylsulfonyl chloride CAS 85952-32-5
| CAS No. | 85952-32-5 |
| Molecular Formula | C8H6ClF3O2S |
| Molecular Weight | 258.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Trifluoromethylbenzylsulfonyl chloride.
CATO supplies 2-Trifluoromethylbenzylsulfonyl chloride (CAS 85952-32-5), a certified reference material (molecular formula C8H6ClF3O2S, MW 258.65 g/mol) for analytical method development and quality control.
2-Trifluoromethylbenzylsulfonyl chloride (C8H6ClF3O2S) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-Trifluoromethylbenzylsulfonyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H6ClF3O2S |
| Molecular Weight | 258.65 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1981 |
| Halogen Content | F/Cl-containing |
| Sulfur Atoms | 1 |
Recommended Standards
- 2-Methyl-5-(trifluoromethyl)benzene-1-sulfonyl chloride (CAS 491850-53-4)
- 4-(2,2,2-trifluoroethyl)benzene-1-sulfonyl chloride (CAS 883146-03-0)
- 1-Chloro-4-(methylsulfonyl)-2-(trifluoromethyl)benzene (CAS 4163-81-9)
- 89520-72-9 Benzene, 1-[(chloromethyl)sulfonyl]-4-(trifluoromethyl)- DTXSID00459514 (CAS 89520-72-9)
- N-((1H-pyrazol-3-yl)methyl)benzo[d][1,3]dioxol-5-amine (CAS 1156316-72-1)
- Aminooxy-PEG3-methyl ester (CAS 2086689-03-2)
- N-((4-Chloro-6-methylpyrimidin-2-yl)methyl)benzamide (CAS 88875-02-9)
- tert-Butyl ((1R,2S,4S)-2-fluoro-4-hydroxycyclohexyl)carbamate (CAS 1932202-56-6)
- Anthragallol (CAS 602-64-2)
- 6-Amino-7-(4-fluorophenoxy)-2,3-dihydrobenzo[b][1,4]dioxine (CAS 1019509-34-2)
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- 1-(4-((4-Chlorophenyl)thio)-3-nitrophenyl)ethan-1-one (CAS 19688-55-2)
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- D-[Phe]6-Liraglutide (CAS CATO-C4X-199235)
Why CATO?
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