5-(difluoromethyl)pyridine-2-carboxylic acid CAS 859538-41-3
| CAS No. | 859538-41-3 |
| Molecular Formula | C7H11F2NO2 |
| Molecular Weight | 179.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
5-(difluoromethyl)pyridine-2-carboxylic acid (CAS 859538-41-3) is a high-purity analytical reference standard with the molecular formula C7H11F2NO2 and a molecular weight of 179.16 g/mol.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, 5-(difluoromethyl)pyridine-2-carboxylic acid is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 179.16 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures 5-(difluoromethyl)pyridine-2-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H11F2NO2 |
| Molecular Weight | 179.16 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related difluoromethyl Standards
- 6-(difluoromethyl)pyridine-3-carboxylic acid (CAS 913091-98-2)
- 2-(Difluoromethyl)quinoline (CAS 1075184-01-8)
- 4-(Difluoromethyl)quinoline (CAS 1186194-77-3)
- 3-(Difluoromethyl)quinoline (CAS 1186195-11-8)
- 5-(Difluoromethyl)isoquinoline (CAS 1204298-57-6)
- 8-(Difluoromethyl)isoquinoline (CAS 1204298-62-3)
- 7-(Difluoromethyl)isoquinoline (CAS 1204298-71-4)
- 6-(Difluoromethyl)isoquinoline (CAS 1204298-75-8)
Recommended Standards
- 4-Amino-3,3-difluorocyclohexane-1-carboxylic acid (CAS 2231676-45-0)
- 5-(Trifluoromethyl)pyridine-2(1H)-thione (CAS 76041-72-0)
- 4-(Trifluoromethylthio)pyridine (CAS 651059-83-5)
- 5-(Trifluoromethyl)pyridine-3-thiol (CAS 912545-82-5)
- 1-Methyl-3-(p-tolyl)tetrahydro-1H-thieno[3,4-d]imidazole-2(3H)-thione 5,5-dioxide (CAS 620543-65-9)
- n-(4-Fluorophenyl)-4-[(methylamino)methyl]piperidine-1-carboxamide hydrochloride (CAS 1423033-82-2)
- 4-(Prop-2-en-1-yloxy)butanoic acid (CAS 44958-10-3)
- 3,6-Diisopropyl-2,7-dimethyloct-4-yne-3,6-diol (CAS 6289-25-4)
- 1-Phenyl-3-(propan-2-yl)-1h-pyrazol-5-amine (CAS 827614-44-8)
- 2-(1,3,4-Thiadiazol-2-yl)ethan-1-amine (CAS 1097305-12-8)
- 3-(Trifluoromethyl)benzoyl cyanide (CAS 77173-53-6)
- 2-(4-(Chloromethyl)phenyl)-5-fluoropyrimidine (CAS 1139432-30-6)
- Truxenone (CAS 4430-15-3)
- Semaglutide impurity 37 (CAS CATO-C4X-222637)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com