tert-butyl (3R,4R)-4-azido-3-hydroxy-piperidine-1-carboxylate CAS 859854-74-3
| CAS No. | 859854-74-3 |
| Molecular Formula | C10H18N4O3 |
| Molecular Weight | 242.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
tert-butyl (3R,4R)-4-azido-3-hydroxy-piperidine-1-carboxylate (CAS 859854-74-3) is a high-purity analytical reference standard with the molecular formula C10H18N4O3 and a molecular weight of 242.27 g/mol.
tert-butyl (3R,4R)-4-azido-3-hydroxy-piperidine-1-carboxylate (C10H18N4O3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), tert-butyl (3R,4R)-4-azido-3-hydroxy-piperidine-1-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H18N4O3 |
| Molecular Weight | 242.27 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 4 |
Recommended Standards
- tert-butyl (3R,4R)-3-azido-4-(hydroxymethyl)pyrrolidine-1-carboxylate (CAS 2416992-86-2)
- tert-butyl (3R,4S)-3-azido-4-methoxy-pyrrolidine-1-carboxylate (CAS 597556-75-7)
- tert-butyl (2S,4S)-4-azido-2-(hydroxymethyl)pyrrolidine-1-carboxylate (CAS 418793-92-7)
- tert-butyl (3S,4R)-3-azido-4-methoxy-pyrrolidine-1-carboxylate (CAS 2381665-49-0)
- 2-amino-3-(4-chlorophenyl)propanoic acid hydrochloride (CAS 23633-07-0)
- 1-(Ethoxymethyl)-6-benzyl-5-isopropyluracil (CAS 149950-60-7)
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